TNIK Antikörper (N-Term)

Produktnummer ABIN392499

Dieses Anti-TNIK-Antikörper ist ein Kaninchen Polyklonal-Antikörper zur Detektion von TNIK in WB und IHC (p). Geeignet für Human und Ratte. Dieses Primary Antibody wurde in 2+ Publikationen zitiert.

Kurzübersicht für TNIK Antikörper (N-Term) (ABIN392499)

Target: TNIK (TRAF2 and NCK Interacting Kinase (TNIK))

Reaktivität: Human, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser TNIK Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Klon: RB3388

Produktdetails anti-TNIK Antikörper

Bindungsspezifität: AA 1-30, N-Term

Aufreinigung: This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.

Immunogen: This TNIK antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 1-30 amino acids from the N-terminal region of human TNIK.

Isotyp: Ig Fraction

Anwendungsinformationen

Applikationshinweise: IHC-P: 1:50~100

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Haltbarkeit: 6 months

Referenzen für anti-TNIK Antikörper (ABIN392499)

Zhang, Jiang, Qin, Su, Cao, Wang: "TNIK serves as a novel biomarker associated with poor prognosis in patients with pancreatic cancer." in: Tumour biology, (2015) (PubMed).

Wang, Charych, Pulito, Lee, Graziane, Crozier, Revilla-Sanchez, Kelly, Dunlop, Murdoch, Taylor, Xie, Pausch, Hayashi-Takagi, Ishizuka, Seshadri, Bates, Kariya, Sawa, Weinberg, Moss, Houslay, Yan et al.: "The psychiatric disease risk factors DISC1 and TNIK interact to regulate synapse composition and function. ..." in: Molecular psychiatry, Vol. 16, Issue 10, pp. 1006-23, (2011) (PubMed).

Details zu TNIK

Target: TNIK (TRAF2 and NCK Interacting Kinase (TNIK))

Andere Bezeichnung: TNIK

Hintergrund: Germinal center kinases (GCKs), such as TNIK, are characterized by an N-terminal kinase domain and a C-terminal GCK domain that serves a regulatory function (Fu et al., 1999 [PubMed 10521462]).[supplied by OMIM]

Molekulargewicht: 154943

Gen-ID: 23043

NCBI Accession: NP_001155032, NP_001155033, NP_001155034, NP_001155035, NP_001155036, NP_001155037, NP_001155038, NP_055843

UniProt: Q9UKE5