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PRKX Antikörper (C-Term)

Dieses Kaninchen Polyklonal-Antikörper erkennt spezifisch PRKX in IHC (p). Er zeigt eine Reaktivität gegenüber Human und Maus und wurde in 1 Publikation erwähnt.
Produktnummer ABIN392449

Kurzübersicht für PRKX Antikörper (C-Term) (ABIN392449)

Target

Alle PRKX Antikörper anzeigen
PRKX (Protein Kinase, X-Linked (PRKX))

Reaktivität

  • 31
  • 20
  • 10
Human, Maus

Wirt

  • 39
  • 4
Kaninchen

Klonalität

  • 41
  • 2
Polyklonal

Konjugat

  • 26
  • 3
  • 2
  • 2
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
Dieser PRKX Antikörper ist unkonjugiert

Applikation

  • 35
  • 20
  • 16
  • 6
  • 5
  • 2
  • 1
Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Klon

RB01029
  • Bindungsspezifität

    • 9
    • 6
    • 5
    • 4
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 312-343, C-Term

    Aufreinigung

    This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.

    Immunogen

    This PRKX antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 312-343 amino acids from the C-terminal region of human PRKX.

    Isotyp

    Ig Fraction
  • Applikationshinweise

    IHC-P: 1:10~50

    Beschränkungen

    Nur für Forschungszwecke einsetzbar
  • Format

    Liquid

    Buffer

    Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

    Konservierungsmittel

    Sodium azide

    Vorsichtsmaßnahmen

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    Lagerung

    4 °C,-20 °C

    Informationen zur Lagerung

    Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.

    Haltbarkeit

    6 months
  • Li, Iomini, Hyink, Wilson: "PRKX critically regulates endothelial cell proliferation, migration, and vascular-like structure formation." in: Developmental biology, Vol. 356, Issue 2, pp. 475-85, (2011) (PubMed).

  • Target

    PRKX (Protein Kinase, X-Linked (PRKX))

    Andere Bezeichnung

    PRKX

    Hintergrund

    Protein kinases are enzymes that transfer a phosphate group from a phosphate donor, generally the g phosphate of ATP, onto an acceptor amino acid in a substrate protein. By this basic mechanism, protein kinases mediate most of the signal transduction in eukaryotic cells, regulating cellular metabolism, transcription, cell cycle progression, cytoskeletal rearrangement and cell movement, apoptosis, and differentiation. With more than 500 gene products, the protein kinase family is one of the largest families of proteins in eukaryotes. The family has been classified in 8 major groups based on sequence comparison of their tyrosine (PTK) or serine/threonine (STK) kinase catalytic domains. The AGC kinase group consists of 63 kinases including the cyclic nucleotide-regulated protein kinase (PKA & PKG) family, the diacylglycerol-activated/phospholipid-dependent protein kinase C (PKC) family, the related to PKA and PKC (RAC/Akt) protein kinase family, the kinases that phosphorylate G protein-coupled receptors family (ARK), and the kinases that phosphorylate ribosomal protein S6 family (RSK). The calcium/calmodulin-dependent kinase (CAMK) group consists of 75 kinases regulated by Ca2+/CaM and close relative family (CAMK, CAMKL, DAPK, MAPKAPK).

    Molekulargewicht

    40896

    Gen-ID

    5613

    NCBI Accession

    NP_005035

    UniProt

    P51817

    Pathways

    Thyroid Hormone Synthesis
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