Amphiregulin Antikörper (C-Term)
Kurzübersicht für Amphiregulin Antikörper (C-Term) (ABIN392202)
Target
Alle Amphiregulin (AREG) Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
Klon
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Bindungsspezifität
- AA 222-252, C-Term
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Aufreinigung
- This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
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Immunogen
- This AREG antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 222-252 amino acids from the C-terminal region of human AREG.
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Isotyp
- Ig Fraction
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Applikationshinweise
- WB: 1:1000. IHC-P: 1:10~50
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Buffer
- Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
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Konservierungsmittel
- Sodium azide
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Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Lagerung
- 4 °C,-20 °C
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Informationen zur Lagerung
- Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.
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Haltbarkeit
- 6 months
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- Amphiregulin (AREG)
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Andere Bezeichnung
- AREG
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Hintergrund
- AREG is a member of the epidermal growth factor family. It is an autocrine growth factor as well as a mitogen for astrocytes, Schwann cells, and fibroblasts. It is related to epidermal growth factor (EGF) and transforming growth factor alpha (TGF-alpha). This protein interacts with the EGF/TGF-alpha receptor to promote the growth of normal epithelial cells and inhibits the growth of certain aggressive carcinoma cell lines. This protein is associated with a psoriasis-like skin phenotype.
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Molekulargewicht
- 27895
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Gen-ID
- 374
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NCBI Accession
- NP_001648
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UniProt
- P15514
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Pathways
- RTK Signalweg, EGFR Signaling Pathway
Target
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