Filamin A Antikörper (AA 1025-1054)

Produktnummer ABIN392193

Dieses Anti-Filamin A-Antikörper ist ein Kaninchen Polyklonal-Antikörper zur Detektion von Filamin A in WB, IHC (p), IF und FACS. Geeignet für Human.

Kurzübersicht für Filamin A Antikörper (AA 1025-1054) (ABIN392193)

Target: Filamin A (FLNA) (Filamin A, alpha (FLNA))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser Filamin A Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (IF), Flow Cytometry (FACS)

Klon: RB14246

Produktdetails anti-Filamin A Antikörper

Bindungsspezifität: AA 1025-1054

Homologie: M

Aufreinigung: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogen: This FLNA antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 1025-1054 amino acids from human FLNA.

Isotyp: Ig Fraction

Anwendungsinformationen

Applikationshinweise: IF: 1:10~50. WB: 1:1000. IHC-P: 1:10~50. FC: 1:10~50

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Haltbarkeit: 6 months

Details zu Filamin A

Target: Filamin A (FLNA) (Filamin A, alpha (FLNA))

Andere Bezeichnung: FLNA

Hintergrund: Actin-binding protein 280, or filamin, is a 280-kD protein that crosslinks actin filaments into orthogonal networks in cortical cytoplasm and participates in the anchoring of membrane proteins for the actin cytoskeleton. Remodeling of the cytoskeleton is central to the modulation of cell shape and migration. Filamin A, encoded by the FLNA gene, is a widely expressed protein that regulates reorganization of the actin cytoskeleton by interacting with integrins, transmembrane receptor complexes, and second messengers.

Molekulargewicht: 280739

Gen-ID: 2316

NCBI Accession: NP_001104026, NP_001447

UniProt: P21333

Pathways: T-Zell Rezeptor Signalweg, Maintenance of Protein Location