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RND3 Antikörper (AA 133-165)

Der Kaninchen Polyklonal Anti-RND3-Antikörper wurde für WB und IHC (p) validiert. Er ist geeignet, RND3 in Proben von Human, Maus und Ratte zu detektieren.
Produktnummer ABIN392162

Kurzübersicht für RND3 Antikörper (AA 133-165) (ABIN392162)

Target

Alle RND3 Antikörper anzeigen
RND3 (rho Family GTPase 3 (RND3))

Reaktivität

  • 31
  • 6
  • 6
  • 2
  • 2
  • 2
  • 2
  • 2
  • 1
  • 1
Human, Maus, Ratte

Wirt

  • 16
  • 15
Kaninchen

Klonalität

  • 17
  • 14
Polyklonal

Konjugat

  • 20
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
Dieser RND3 Antikörper ist unkonjugiert

Applikation

  • 16
  • 15
  • 9
  • 5
  • 2
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Klon

RB14500
  • Bindungsspezifität

    • 5
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 133-165

    Homologie

    Pig

    Aufreinigung

    This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.

    Immunogen

    This ARHE antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 133-165 amino acids from the Central region of human ARHE.

    Isotyp

    Ig Fraction
  • Applikationshinweise

    WB: 1:2000. WB: 1:1000. IHC-P: 1:10~50

    Beschränkungen

    Nur für Forschungszwecke einsetzbar
  • Format

    Liquid

    Buffer

    Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

    Konservierungsmittel

    Sodium azide

    Vorsichtsmaßnahmen

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    Lagerung

    4 °C,-20 °C

    Informationen zur Lagerung

    Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.

    Haltbarkeit

    6 months
  • Target

    RND3 (rho Family GTPase 3 (RND3))

    Andere Bezeichnung

    ARHE

    Hintergrund

    Members of the Rho family of Ras-related GTPases, such as ARHE, regulate the organization of the actin cytoskeleton in response to extracellular growth factors. Like Ras (MIM 190020), Rho family members appear to cycle between an inactive GDP-bound form and an active GTP-bound form. Three major regulators of Rho activity have been identified: RhoGDIs, which interact with the GDP-bound Rho proteins to keep them in a resting complex (see MIM 601925), GEFs, which promote GDP/GTP exchange leading to activation of Rho proteins (see MIM 601855), and GAPs, which stimulate GTP hydrolysis and return the activated Rho protein to its inactive form (see MIM 602680) (Nobes et al., 1998 [PubMed 9531558]).

    Molekulargewicht

    27368

    Gen-ID

    390

    NCBI Accession

    NP_001241667, NP_005159

    UniProt

    P61587
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