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TEK Antikörper (C-Term)

Dieses Kaninchen Polyklonal-Antikörper erkennt spezifisch TEK in WB und IHC (p). Er zeigt eine Reaktivität gegenüber Human.
Produktnummer ABIN392059

Kurzübersicht für TEK Antikörper (C-Term) (ABIN392059)

Target

Alle TEK Antikörper anzeigen
TEK (TEK Tyrosine Kinase, Endothelial (TEK))

Reaktivität

  • 136
  • 73
  • 50
  • 22
  • 4
  • 3
Human

Wirt

  • 124
  • 30
  • 8
  • 3
  • 2
Kaninchen

Klonalität

  • 130
  • 37
Polyklonal

Konjugat

  • 85
  • 12
  • 8
  • 8
  • 4
  • 4
  • 3
  • 3
  • 3
  • 3
  • 3
  • 3
  • 3
  • 3
  • 3
  • 3
  • 3
  • 3
  • 3
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
Dieser TEK Antikörper ist unkonjugiert

Applikation

  • 88
  • 59
  • 44
  • 40
  • 40
  • 38
  • 24
  • 18
  • 13
  • 13
  • 9
  • 7
  • 4
  • 4
  • 2
  • 2
  • 2
  • 1
Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Klon

RB01525-01526
  • Bindungsspezifität

    • 20
    • 19
    • 16
    • 8
    • 7
    • 7
    • 6
    • 5
    • 4
    • 4
    • 4
    • 4
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 758-789, C-Term

    Homologie

    B

    Aufreinigung

    This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.

    Immunogen

    This TEK (TIE2) antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 758-789 amino acids from the C-terminal region of human TEK (TIE2).

    Isotyp

    Ig Fraction
  • Applikationshinweise

    WB: 1:1000. IHC-P: 1:50~100. IHC-P: 1:50~100

    Beschränkungen

    Nur für Forschungszwecke einsetzbar
  • Format

    Liquid

    Buffer

    Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

    Konservierungsmittel

    Sodium azide

    Vorsichtsmaßnahmen

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    Lagerung

    4 °C,-20 °C

    Informationen zur Lagerung

    Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.

    Haltbarkeit

    6 months
  • Target

    TEK (TEK Tyrosine Kinase, Endothelial (TEK))

    Andere Bezeichnung

    TEK (TIE2)

    Hintergrund

    The TEK receptor tyrosine kinase is expressed almost exclusively in endothelial cells in mice, rats, and humans. This receptor possesses a unique extracellular domain containing 2 immunoglobulin-like loops separated by 3 epidermal growth factor-like repeats that are connected to 3 fibronectin type III-like repeats. The ligand for the receptor is angiopoietin-1. Defects in TEK are associated with inherited venous malformations, the TEK signaling pathway appears to be critical for endothelial cell-smooth muscle cell communication in venous morphogenesis. TEK is closely related to the TIE receptor tyrosine kinase.

    Molekulargewicht

    125830

    Gen-ID

    7010

    NCBI Accession

    NP_000450

    UniProt

    Q02763

    Pathways

    RTK Signalweg, Growth Factor Binding
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