Telefon:
+49 (0)241 95 163 153
Fax:
+49 (0)241 95 163 155
E-Mail:
orders@antikoerper-online.de

ErbB2/Her2 Antikörper (C-Term)

Dieses Anti-ErbB2/Her2-Antikörper ist ein Kaninchen Polyklonal-Antikörper zur Detektion von ErbB2/Her2 in WB und IHC (p). Geeignet für Human.
Produktnummer ABIN391947

Kurzübersicht für ErbB2/Her2 Antikörper (C-Term) (ABIN391947)

Target

Alle ErbB2/Her2 Antikörper anzeigen
ErbB2/Her2 (Receptor tyrosine-protein kinase erbB-2 (ErbB2/Her2))

Reaktivität

  • 543
  • 130
  • 122
  • 33
  • 8
  • 5
  • 3
  • 3
  • 3
  • 3
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
Human

Wirt

  • 300
  • 259
  • 10
  • 6
  • 3
  • 2
  • 2
  • 1
Kaninchen

Klonalität

  • 294
  • 284
  • 3
Polyklonal

Konjugat

  • 320
  • 33
  • 22
  • 14
  • 11
  • 11
  • 11
  • 11
  • 11
  • 11
  • 8
  • 8
  • 8
  • 8
  • 8
  • 8
  • 8
  • 8
  • 8
  • 8
  • 7
  • 7
  • 5
  • 5
  • 4
  • 4
  • 4
  • 4
  • 3
  • 2
  • 1
  • 1
Dieser ErbB2/Her2 Antikörper ist unkonjugiert

Applikation

  • 316
  • 206
  • 141
  • 135
  • 117
  • 93
  • 84
  • 80
  • 75
  • 60
  • 54
  • 47
  • 30
  • 12
  • 9
  • 8
  • 6
  • 5
  • 3
  • 3
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Klon

RB15814
  • Bindungsspezifität

    • 87
    • 32
    • 30
    • 30
    • 25
    • 25
    • 23
    • 17
    • 17
    • 15
    • 13
    • 13
    • 10
    • 7
    • 6
    • 6
    • 5
    • 5
    • 5
    • 4
    • 4
    • 4
    • 4
    • 4
    • 4
    • 4
    • 4
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    AA 1227-1255, C-Term

    Homologie

    M, Rat

    Aufreinigung

    This antibody is purified through a protein A column, followed by peptide affinity purification.

    Immunogen

    This ERBB2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 1227-1255 amino acids from the C-terminal region of human ERBB2.

    Isotyp

    Ig Fraction
  • Applikationshinweise

    WB: 1:1000. WB: 1:1000. IHC-P: 1:10~50

    Beschränkungen

    Nur für Forschungszwecke einsetzbar
  • Format

    Liquid

    Buffer

    Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

    Konservierungsmittel

    Sodium azide

    Vorsichtsmaßnahmen

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    Lagerung

    4 °C,-20 °C

    Informationen zur Lagerung

    Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.

    Haltbarkeit

    6 months
  • Target

    ErbB2/Her2 (Receptor tyrosine-protein kinase erbB-2 (ErbB2/Her2))

    Andere Bezeichnung

    ERBB2

    Hintergrund

    ErbB2, a member of the EGF receptor family, is an essential component of a neuregulin-receptor complex, although neuregulins do not interact with it alone. GP30 is a potential ligand for this receptor. This protein is not activated by EGF, TGF-alpha and amphiregulin. ErbB2 potentially forms a heterodimer with each of the other ERBB receptors. An interaction with PRKCABP has been suggested. Ligand-binding to this Type I membrane protein may increase phosphorylation on tyrosine residues.

    Molekulargewicht

    137910

    Gen-ID

    2064

    NCBI Accession

    NP_001005862, NP_004439

    UniProt

    P04626

    Pathways

    RTK Signalweg, Fc-epsilon Rezeptor Signalübertragung, EGFR Signaling Pathway, Neurotrophin Signalübertragung, Skeletal Muscle Fiber Development
Sie sind hier:
Chat with us!