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EPH Receptor B2 Antikörper

This anti-EPH Receptor B2 antibody (ABIN391921) is a Rabbit Polyclonal antibody detecting EPH Receptor B2 in WB, FACS, IHC (p). Suitable for Human.
Produktnummer ABIN391921

Kurzübersicht für EPH Receptor B2 Antikörper (ABIN391921)

Target

Alle EPH Receptor B2 (EPHB2) Antikörper anzeigen
EPH Receptor B2 (EPHB2)

Reaktivität

  • 61
  • 31
  • 14
  • 6
  • 2
  • 1
  • 1
Human

Wirt

  • 48
  • 16
  • 5
  • 2
Kaninchen

Klonalität

  • 50
  • 21
Polyklonal

Konjugat

  • 42
  • 6
  • 5
  • 5
  • 4
  • 3
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
Dieser EPH Receptor B2 Antikörper ist unkonjugiert

Applikation

  • 48
  • 48
  • 26
  • 15
  • 13
  • 10
  • 10
  • 2
  • 2
  • 2
  • 1
  • 1
  • 1
Western Blotting (WB), Flow Cytometry (FACS), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Klon

RB15188
  • Aufreinigung

    This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.

    Immunogen

    This EphB2 antibody is generated from rabbits immunized with a recombinant human EphB2 protein.

    Isotyp

    Ig Fraction
  • Applikationshinweise

    WB: 1:1000. IHC-P: 1:10~50. FC: 1:10~50

    Beschränkungen

    Nur für Forschungszwecke einsetzbar
  • Format

    Liquid

    Buffer

    Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

    Konservierungsmittel

    Sodium azide

    Vorsichtsmaßnahmen

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    Lagerung

    4 °C,-20 °C

    Informationen zur Lagerung

    Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.

    Haltbarkeit

    6 months
  • Target

    EPH Receptor B2 (EPHB2)

    Andere Bezeichnung

    EphB2

    Hintergrund

    Ephrin receptors and their ligands, the ephrins, mediate numerous developmental processes, particularly in the nervous system. Based on their structures and sequence relationships, ephrins are divided into the ephrin-A (EFNA) class, which are anchored to the membrane by a glycosylphosphatidylinositol linkage, and the ephrin-B (EFNB) class, which are transmembrane proteins. The Eph family of receptors are divided into 2 groups based on the similarity of their extracellular domain sequences and their affinities for binding ephrin-A and ephrin-B ligands. Ephrin receptors make up the largest subgroup of the receptor tyrosine kinase (RTK) family. The ligand-activated form of EphB2, which belongs to the Tyr family of protein kinases, interacts with multiple proteins, including GTPase-activating protein (RASGAP) through its SH2 domain. It binds RASGAP through the juxtamembrane tyrosines residues, and also interacts with PRKCABP and GRIP1 This type I membrane protein is expressed in brain, heart, lung, kidney, placenta, pancreas, liver and skeletal muscle. It is preferentially expressed in fetal brain. This protein contains putatively 2 fibronectin type III domains and 1 sterile alpha motif (SAM) domain.

    Molekulargewicht

    117493

    Gen-ID

    2048

    NCBI Accession

    NP_004433, NP_059145

    UniProt

    P29323

    Pathways

    RTK Signalweg, Regulation of long-term Neuronal Synaptic Plasticity, S100 Proteine
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