YARS Antikörper (N-Term)

Produktnummer ABIN391838

Der Kaninchen Polyklonal Anti-YARS-Antikörper wurde für WB validiert. Er ist geeignet, YARS in Proben von Human zu detektieren. Es ist 1 Publikation verfügbar.

Kurzübersicht für YARS Antikörper (N-Term) (ABIN391838)

Target: YARS (Yars) (Tyrosyl-tRNA Synthetase (Yars))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser YARS Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Klon: RB14873

Produktdetails anti-YARS Antikörper

Bindungsspezifität: AA 160-190, N-Term

Homologie: Rat

Aufreinigung: This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.

Immunogen: This Tyrosyl tRNA synthetase (YARS) antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 160-190 amino acids from the N-terminal region of human Tyrosyl tRNA synthetase (YARS).

Isotyp: Ig Fraction

Anwendungsinformationen

Applikationshinweise: WB: 1:1000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Haltbarkeit: 6 months

Referenzen für anti-YARS Antikörper (ABIN391838)

Wei, Xu, Liu, Lo, Ye, Lau, Wang, Zhou, Nangle, Yang, Zhang, Schimmel: "Alternative splicing creates two new architectures for human tyrosyl-tRNA synthetase." in: Nucleic acids research, Vol. 44, Issue 3, pp. 1247-55, (2016) (PubMed).

Details zu YARS

Target: YARS (Yars) (Tyrosyl-tRNA Synthetase (Yars))

Andere Bezeichnung: Tyrosyl tRNA synthetase (YARS)

Hintergrund: Aminoacyl-tRNA synthetases catalyze the aminoacylation of tRNA by their cognate amino acid. Because of their central role in linking amino acids with nucleotide triplets contained in tRNAs, aminoacyl-tRNA synthetases are thought to be among the first proteins that appeared in evolution. Tyrosyl-tRNA synthetase belongs to the class I tRNA synthetase family. Cytokine activities have also been observed for the human tyrosyl-tRNA synthetase, after it is split into two parts, an N-terminal fragment that harbors the catalytic site and a C-terminal fragment found only in the mammalian enzyme. The N-terminal fragment is an interleukin-8-like cytokine, whereas the released C-terminal fragment is an EMAP II-like cytokine.

Molekulargewicht: 59143

Gen-ID: 8565

NCBI Accession: NP_003671

UniProt: P54577