Telefon:
+49 (0)241 95 163 153
Fax:
+49 (0)241 95 163 155
E-Mail:
orders@antikoerper-online.de

Cullin 5 Antikörper (C-Term)

Dieses Kaninchen Polyklonal-Antikörper erkennt spezifisch Cullin 5 in WB, IHC (p) und FACS. Er zeigt eine Reaktivität gegenüber Human.
Produktnummer ABIN391834

Kurzübersicht für Cullin 5 Antikörper (C-Term) (ABIN391834)

Target

Alle Cullin 5 (CUL5) Antikörper anzeigen
Cullin 5 (CUL5)

Reaktivität

  • 38
  • 14
  • 11
  • 6
  • 4
  • 4
  • 4
  • 3
  • 3
  • 2
  • 2
  • 2
  • 1
  • 1
  • 1
Human

Wirt

  • 37
  • 1
Kaninchen

Klonalität

  • 38
Polyklonal

Konjugat

  • 24
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
Dieser Cullin 5 Antikörper ist unkonjugiert

Applikation

  • 20
  • 13
  • 13
  • 13
  • 6
  • 6
  • 4
  • 3
  • 3
  • 2
  • 2
  • 2
  • 1
  • 1
Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Flow Cytometry (FACS)

Klon

RB17926
  • Bindungsspezifität

    • 15
    • 5
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 747-774, C-Term

    Homologie

    Rb

    Aufreinigung

    This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.

    Immunogen

    This CUL5 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 747-774 amino acids from the C-terminal region of human CUL5.

    Isotyp

    Ig Fraction
  • Applikationshinweise

    WB: 1:1000. IHC-P: 1:50~100. FC: 1:10~50

    Beschränkungen

    Nur für Forschungszwecke einsetzbar
  • Format

    Liquid

    Buffer

    Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

    Konservierungsmittel

    Sodium azide

    Vorsichtsmaßnahmen

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    Lagerung

    4 °C,-20 °C

    Informationen zur Lagerung

    Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.

    Haltbarkeit

    6 months
  • Target

    Cullin 5 (CUL5)

    Andere Bezeichnung

    CUL5

    Hintergrund

    CUL5 is a core component of multiple SCF-like ECS (Elongin-Cullin 2/5-SOCS-box protein) E3 ubiquitin-protein ligase complexes, which mediate the ubiquitination and subsequent proteasomal degradation of target proteins. As a scaffold protein may contribute to catalysis through positioning of the substrate and the ubiquitin-conjugating enzyme. The functional specificity of the E3 ubiquitin-protein ligase complex depends on the variable substrate recognition component. ECS(SOCS1) seems to direct ubiquitination of JAk2. It seems to be involved poteosomal degradation of p53/TP53 stimulated by adenovirus E1B-55 kDa protein and may form a cell surface vasopressin receptor.

    Molekulargewicht

    90955

    Gen-ID

    8065

    NCBI Accession

    NP_003469

    UniProt

    Q93034

    Pathways

    Regulation of Muscle Cell Differentiation, Skeletal Muscle Fiber Development
Sie sind hier:
Chat with us!