Vinculin Antikörper (C-Term)

Produktnummer ABIN391626

Dieses Anti-Vinculin-Antikörper ist ein Kaninchen Polyklonal-Antikörper zur Detektion von Vinculin in WB. Geeignet für Human und Maus.

Kurzübersicht für Vinculin Antikörper (C-Term) (ABIN391626)

Target: Vinculin (VCL)

Reaktivität: Human, Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser Vinculin Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Klon: RB16690

Produktdetails anti-Vinculin Antikörper

Bindungsspezifität: AA 1012-1039, C-Term

Homologie: C, Pig, Rat

Aufreinigung: This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.

Immunogen: This VINC antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 1012-1039 amino acids from the C-terminal region of human VINC.

Isotyp: Ig Fraction

Anwendungsinformationen

Applikationshinweise: WB: 1:1000. WB: 1:1000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Haltbarkeit: 6 months

Details zu Vinculin

Target: Vinculin (VCL)

Andere Bezeichnung: Vinculin

Hintergrund: VINC is a cytoskeletal protein associated with cell-cell and cell-matrix junctions, where it is thought to function as one of several interacting proteins involved in anchoring F-actin to the membrane. Defects in VCL are the cause of cardiomyopathy dilated type 1W. Dilated cardiomyopathy is a disorder characterized by ventricular dilation and impaired systolic function, resulting in congestive heart failure and arrhythmia.

Molekulargewicht: 123799

Gen-ID: 7414

NCBI Accession: NP_003364, NP_054706

UniProt: P18206

Pathways: Cell-Cell Junction Organization, Maintenance of Protein Location, Signaling Events mediated by VEGFR1 and VEGFR2