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Prohibitin 2 Antikörper (N-Term)

PHB2 Reaktivität: Human WB, IHC (p) Wirt: Kaninchen Polyclonal RB10629 unconjugated
Produktnummer ABIN2841408
  • Target Alle Prohibitin 2 (PHB2) Antikörper anzeigen
    Prohibitin 2 (PHB2)
    Bindungsspezifität
    • 16
    • 8
    • 8
    • 8
    • 8
    • 5
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 66-95, N-Term
    Reaktivität
    • 76
    • 40
    • 15
    • 11
    • 8
    • 8
    • 7
    • 5
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    Human
    Wirt
    • 74
    • 2
    • 2
    Kaninchen
    Klonalität
    • 75
    • 3
    Polyklonal
    Konjugat
    • 48
    • 4
    • 4
    • 4
    • 3
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser Prohibitin 2 Antikörper ist unkonjugiert
    Applikation
    • 67
    • 25
    • 22
    • 18
    • 17
    • 13
    • 13
    • 10
    • 10
    • 9
    • 5
    • 3
    • 2
    • 2
    • 2
    • 1
    Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
    Homologie
    B, C, M, Rat
    Aufreinigung
    This antibody is purified through a protein A column, followed by peptide affinity purification.
    Immunogen
    This REA (PHB2) antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 66-95 amino acids from the N-terminal region of human REA (PHB2).
    Klon
    RB10629
    Isotyp
    Ig Fraction
    Top Product
    Discover our top product PHB2 Primärantikörper
  • Applikationshinweise
    WB: 1:1000. IHC-P: 1:10~50
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Buffer
    Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Lagerung
    4 °C,-20 °C
    Informationen zur Lagerung
    Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.
    Haltbarkeit
    6 months
  • Target
    Prohibitin 2 (PHB2)
    Andere Bezeichnung
    REA (PHB2) (PHB2 Produkte)
    Synonyme
    bcap37 antikoerper, zgc:73150 antikoerper, wu:fc28c08 antikoerper, PHB2 antikoerper, phb2 antikoerper, ATPHB2 antikoerper, F21M11.21 antikoerper, F21M11_21 antikoerper, prohibitin 2 antikoerper, DKFZp469N1310 antikoerper, BAP antikoerper, BCAP37 antikoerper, Bap37 antikoerper, PNAS-141 antikoerper, REA antikoerper, p22 antikoerper, bap37 antikoerper, prohibitin2 antikoerper, xphb2 antikoerper, AU044498 antikoerper, Bcap37 antikoerper, Bap antikoerper, Bap-37 antikoerper, Bcap27 antikoerper, prohibitin 2a antikoerper, prohibitin 2 antikoerper, prohibitin 2 S homeolog antikoerper, phb2a antikoerper, PHB2 antikoerper, phb2 antikoerper, phb2.S antikoerper, Phb2 antikoerper
    Hintergrund
    PHB2 acts as a mediator of transcriptional repression by nuclear hormone receptors via recruitment of histone deacetylases. This protein functions as an estrogen receptor (ER)-selective coregulator that potentiates the inhibitory activities of antiestrogens and represses the activity of estrogens. It competes with NCOA1 for modulation of ER transcriptional activity. It is probably involved in regulating mitochondrial respiration activity and in aging.
    Molekulargewicht
    33296
    Gen-ID
    11331
    NCBI Accession
    NP_001138303, NP_001254629
    UniProt
    Q99623
    Pathways
    Intracellular Steroid Hormone Receptor Signaling Pathway, Regulation of Intracellular Steroid Hormone Receptor Signaling
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