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LKB1 Antikörper (N-Term)

Zitiert in 1 Publikation. Der Kaninchen Polyklonal anti-LKB1 Antikörper (Klon RB3547) (ABIN391350) detektiert spezifisch LKB1 in WB, IF, IHC (p) und FACS. Dieser Antikörper reagiert spezifisch mit Proben aus Human.

STK11 (LKB1) Antibody (N-term I29) (ABIN391350 and ABIN2841371) flow cytometric analysis of NCI- cells (right histogram) compared to a negative control cell (left histogram). (LKB1 Antikörper (N-Term))

FACS

Confocal immunofluorescent analysis of STK11 (LKB1) Antibody (N-term I29) (ABIN391350 and ABIN2841371) with ZR-75-1 cell followed by Alexa Fluor 488-conjugated goat anti-rabbit lgG (green). (LKB1 Antikörper (N-Term))

STK11 Antibody (I29) (ABIN391350 and ABIN2841371) western blot analysis in T47D cell line lysates (35 μg/lane). (LKB1 Antikörper (N-Term))

Formalin-fixed and paraffin-embedded human cancer tissue reacted with the primary antibody, which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. (LKB1 Antikörper (N-Term))

IHC (p)

5 Abbildungen

(1 reference)

Produktnummer ABIN391350

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Kurzübersicht für LKB1 Antikörper (N-Term) (ABIN391350)

Target

Alle LKB1 (STK11) Antikörper anzeigen

LKB1 (STK11) (serine/threonine Kinase 11 (STK11))

Reaktivität

Human

Wirt

Kaninchen

Klonalität

Polyklonal

Konjugat

Dieser LKB1 Antikörper ist unkonjugiert

Applikation

Western Blotting (WB), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Flow Cytometry (FACS)

Klon

RB3547

Discover our top product STK11 Primärantikörper

Bindungsspezifität
21

19

18

15

15

15

8

7

7

6

2

2

2

2

2

2

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1
AA 14-44, N-Term

Homologie

C, M, Rat, X

Aufreinigung

This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.

Immunogen

This STK11 (LKB1) antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 14-44 amino acids from the N-terminal region of human STK11 (LKB1).

Isotyp

Ig Fraction
anti-serine/threonine Kinase 11 (STK11) (AA 134-433) antibody
STK11 Reaktivität: Human WB, IHC, IF Wirt: Kaninchen Polyclonal unconjugated

anti-serine/threonine Kinase 11 (STK11) (AA 14-44) antibody
STK11 Reaktivität: Human WB, ELISA, IHC, IF, FACS Wirt: Kaninchen Polyclonal unconjugated

anti-serine/threonine Kinase 11 (STK11) (AA 393-420), (C-Term) antibody
STK11 Reaktivität: Maus WB, IF, IHC (p) Wirt: Kaninchen Polyclonal RB37144 unconjugated

anti-serine/threonine Kinase 11 (STK11) (pSer428) antibody
STK11 Reaktivität: Human, Maus WB, ELISA, IHC, IF, ICC Wirt: Kaninchen Polyclonal unconjugated

anti-serine/threonine Kinase 11 (STK11) (AA 19-48) antibody
STK11 Reaktivität: Human WB, ELISA, IF, FACS Wirt: Kaninchen Polyclonal unconjugated

anti-serine/threonine Kinase 11 (STK11) (pThr189) antibody
STK11 Reaktivität: Human, Maus WB, ELISA, IF, ICC Wirt: Kaninchen Polyclonal unconjugated

anti-serine/threonine Kinase 11 (STK11) (Internal Region) antibody
STK11 Reaktivität: Human, Maus, Ratte WB, ELISA, IF, ICC Wirt: Kaninchen Polyclonal unconjugated

anti-serine/threonine Kinase 11 (STK11) antibody
STK11 Reaktivität: Human, Maus, Affe WB, ELISA, FACS Wirt: Maus Monoclonal 4H12 unconjugated

anti-serine/threonine Kinase 11 (STK11) (AA 1-433) antibody
STK11 Reaktivität: Human WB, IF, PLA Wirt: Kaninchen Polyclonal unconjugated

anti-serine/threonine Kinase 11 (STK11) (N-Term) antibody
STK11 Reaktivität: Human, Maus WB, IHC, IHC (p) Wirt: Kaninchen Polyclonal unconjugated

Applikationshinweise

IF: 1:10~50. WB: 1:1000. WB: 1:1000. IHC-P: 1:50~100. FC: 1:10~50

Beschränkungen

Nur für Forschungszwecke einsetzbar
Format

Liquid

Buffer

Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Konservierungsmittel

Sodium azide

Vorsichtsmaßnahmen

This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung

4 °C,-20 °C

Informationen zur Lagerung

Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C.

Haltbarkeit

6 months
Sohn, Jang, Campan, Weisenberger, Dickhout, Wang, Cho, Yates, Lucock, Chiang, Austin, Choi, Laird, Kim et al.: "The methylenetetrahydrofolate reductase C677T mutation induces cell-specific changes in genomic DNA methylation and uracil misincorporation: a possible molecular basis for the site-specific cancer ..." in: International journal of cancer. Journal international du cancer, Vol. 124, Issue 9, pp. 1999-2005, (2009) (PubMed).
Target

LKB1 (STK11) (serine/threonine Kinase 11 (STK11))

Andere Bezeichnung

STK11 (LKB1)

Hintergrund

STK11, is a member of the serine/threonine kinase family, regulates cell polarity and functions as a tumor suppressor. Mutations in STK11 have been associated with Peutz-Jeghers syndrome, an autosomal dominant disorder characterized by the growth of polyps in the gastrointestinal tract, pigmented macules on the skin and mouth, and other neoplasms.

Molekulargewicht

48636

NCBI Accession

NP_000446

UniProt

Q15831

Pathways

AMPK Signaling, Carbohydrate Homeostasis, Regulation of Carbohydrate Metabolic Process, Warburg Effekt