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Aurora Kinase C Antikörper (N-Term)

Der Kaninchen Polyklonal Anti-Aurora Kinase C-Antikörper wurde für WB und IHC (p) validiert. Er ist geeignet, Aurora Kinase C in Proben von Human zu detektieren.
Produktnummer ABIN390977

Kurzübersicht für Aurora Kinase C Antikörper (N-Term) (ABIN390977)

Target

Alle Aurora Kinase C (AURKC) Antikörper anzeigen
Aurora Kinase C (AURKC)

Reaktivität

  • 68
  • 30
  • 18
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
Human

Wirt

  • 68
  • 4
  • 1
Kaninchen

Klonalität

  • 71
  • 2
Polyklonal

Konjugat

  • 39
  • 5
  • 4
  • 4
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
Dieser Aurora Kinase C Antikörper ist unkonjugiert

Applikation

  • 60
  • 31
  • 21
  • 16
  • 15
  • 5
  • 2
  • 1
Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Klon

RB6505
  • Bindungsspezifität

    • 9
    • 8
    • 7
    • 6
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 1-30, N-Term

    Aufreinigung

    This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.

    Immunogen

    This Aurora-C antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 1-30 amino acids from the N-terminal region of human Aurora-C.

    Isotyp

    Ig Fraction
  • Applikationshinweise

    WB: 1:1000. IHC-P: 1:100

    Beschränkungen

    Nur für Forschungszwecke einsetzbar
  • Format

    Liquid

    Buffer

    Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

    Konservierungsmittel

    Sodium azide

    Vorsichtsmaßnahmen

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    Lagerung

    4 °C,-20 °C

    Informationen zur Lagerung

    Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.

    Haltbarkeit

    6 months
  • Target

    Aurora Kinase C (AURKC)

    Andere Bezeichnung

    Aurora-C

    Hintergrund

    Chromosomal segregation during mitosis as well as meiosis is regulated by kinases and phosphatases. The Aurora kinases, members of the Ser/Thr protein kinase family, associate with microtubules during chromosome movement and segregation. Aurora kinase C may play a part in organizing microtubules in relation to the function of the centrosome/spindle pole during mitosis. This protein is localized to centrosome from anaphase to cytokinesis. Expression is limited to testis in normal cells. Elevated expression levels are seen only in a subset of cancer cells such as HepG2, HuH7 and HeLa cells. Aurora-C expression is maximum at M phase.

    Molekulargewicht

    35591

    Gen-ID

    6795

    NCBI Accession

    NP_001015878, NP_001015879, NP_003151

    UniProt

    Q9UQB9

    Pathways

    Zellzyklus, Maintenance of Protein Location
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