VCP Antikörper (C-Term)

Produktnummer ABIN390907

Dieser Kaninchen Polyklonal Antikörper detektiert spezifisch VCP in WB, FACS und IHC (p). Es zeigt Reaktivität gegenüber Proben von Human.Es wurde in 1 Publikation zitiert.

Kurzübersicht für VCP Antikörper (C-Term) (ABIN390907)

Target: VCP (Valosin Containing Protein (VCP))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser VCP Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Flow Cytometry (FACS), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Klon: RB21276

Produktdetails anti-VCP Antikörper

Bindungsspezifität: AA 726-755, C-Term

Homologie: B, Zf, M, Pig, Rat, X

Aufreinigung: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogen: This VCP antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 726-755 amino acids from the C-terminal region of human VCP.

Isotyp: Ig Fraction

Anwendungsinformationen

Applikationshinweise: WB: 1:1000. IHC-P: 1:50~100. FC: 1:10~50

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Haltbarkeit: 6 months

Referenzen für anti-VCP Antikörper (ABIN390907)

Ayaki, Ito, Fukushima, Inoue, Kondo, Ikemoto, Asano, Shodai, Fujita, Fukui, Morino, Nakano, Kusaka, Yamashita, Ihara, Matsumoto, Kawamata, Urushitani, Kawakami, Takahashi: "Immunoreactivity of valosin-containing protein in sporadic amyotrophic lateral sclerosis and in a case of its novel mutant." in: Acta neuropathologica communications, Vol. 2, pp. 172, (2015) (PubMed).

Details zu VCP

Target: VCP (Valosin Containing Protein (VCP))

Andere Bezeichnung: VCP

Hintergrund: VCP is a member of a family that includes putative ATP-binding proteins involved in vesicle transport and fusion, 26S proteasome function, and assembly of peroxisomes. This protein, as a structural protein, is associated with clathrin, and heat-shock protein Hsc70, to form a complex. It has been implicated in a number of cellular events that are regulated during mitosis, including homotypic membrane fusion, spindle pole body function, and ubiquitin-dependent protein degradation.

Molekulargewicht: 89322

Gen-ID: 7415

NCBI Accession: NP_009057

UniProt: P55072

Pathways: ER-Nucleus Signaling, Positive Regulation of Endopeptidase Activity, Ubiquitin Proteasome Pathway