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Caldesmon Antikörper (AA 428-457)

Der Kaninchen Polyklonal Anti-Caldesmon-Antikörper wurde für WB, FACS und IHC (p) validiert. Er ist geeignet, Caldesmon in Proben von Human zu detektieren.
Produktnummer ABIN390542

Kurzübersicht für Caldesmon Antikörper (AA 428-457) (ABIN390542)

Target

Alle Caldesmon (CALD1) Antikörper anzeigen
Caldesmon (CALD1) (Caldesmon 1 (CALD1))

Reaktivität

  • 111
  • 95
  • 62
  • 5
  • 4
  • 4
  • 4
  • 3
  • 2
  • 2
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
Human

Wirt

  • 117
  • 31
Kaninchen

Klonalität

  • 99
  • 49
Polyklonal

Konjugat

  • 82
  • 6
  • 6
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
Dieser Caldesmon Antikörper ist unkonjugiert

Applikation

  • 99
  • 64
  • 32
  • 27
  • 27
  • 26
  • 21
  • 21
  • 17
  • 12
  • 12
  • 7
  • 5
  • 4
  • 3
  • 2
  • 1
Western Blotting (WB), Flow Cytometry (FACS), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Klon

RB19749
  • Bindungsspezifität

    • 24
    • 19
    • 15
    • 6
    • 4
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 428-457

    Aufreinigung

    This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.

    Immunogen

    This CALD1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 428-457 amino acids from the Central region of human CALD1.

    Isotyp

    Ig Fraction
  • Applikationshinweise

    WB: 1:1000. IHC-P: 1:10~50. FC: 1:10~50

    Beschränkungen

    Nur für Forschungszwecke einsetzbar
  • Format

    Liquid

    Buffer

    Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

    Konservierungsmittel

    Sodium azide

    Vorsichtsmaßnahmen

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    Lagerung

    4 °C,-20 °C

    Informationen zur Lagerung

    Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.

    Haltbarkeit

    6 months
  • Target

    Caldesmon (CALD1) (Caldesmon 1 (CALD1))

    Andere Bezeichnung

    CALD1

    Hintergrund

    CALD1 is a calmodulin- and actin-binding protein that plays an essential role in the regulation of smooth muscle and nonmuscle contraction. The conserved domain of this protein possesses the binding activities to Ca(2+)-calmodulin, actin, tropomyosin, myosin, and phospholipids. This protein is a potent inhibitor of the actin-tropomyosin activated myosin MgATPase, and serves as a mediating factor for Ca(2+)-dependent inhibition of smooth muscle contraction.

    Molekulargewicht

    93231

    Gen-ID

    800

    NCBI Accession

    NP_004333, NP_149129, NP_149130, NP_149131, NP_149347

    UniProt

    Q05682

    Pathways

    Myometrial Relaxation and Contraction
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