RCAN1 Antikörper (AA 75-104)

Produktnummer ABIN390297

Dieses Anti-RCAN1-Antikörper ist ein Kaninchen Polyklonal-Antikörper zur Detektion von RCAN1 in WB. Geeignet für Human.

Kurzübersicht für RCAN1 Antikörper (AA 75-104) (ABIN390297)

Target: RCAN1 (Regulator of Calcineurin 1 (RCAN1))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser RCAN1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Klon: RB2181

Produktdetails anti-RCAN1 Antikörper

Bindungsspezifität: AA 75-104

Aufreinigung: This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.

Immunogen: This DSCR1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 75-104 amino acids from the Central region of human DSCR1.

Isotyp: Ig Fraction

Anwendungsinformationen

Applikationshinweise: WB: 1:1000. WB: 1:1000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Haltbarkeit: 6 months

Details zu RCAN1

Target: RCAN1 (Regulator of Calcineurin 1 (RCAN1))

Andere Bezeichnung: DSCR1

Hintergrund: DSCR1 (calcipressin 1) interacts with calcineurin A and inhibits calcineurin-dependent signaling pathways, possibly affecting central nervous system development. Thr gene for this protein is located in the minimal candidate region for the Down syndrome phenotype, and is overexpressed in the brain of Down syndrome fetuses. Chronic overexpression of this gene may lead to neurofibrillary tangles such as those associated with Alzheimer disease.

Molekulargewicht: 28079

Gen-ID: 1827

NCBI Accession: NP_004405, NP_981962, NP_981963

UniProt: P53805

Pathways: Regulation of Muscle Cell Differentiation, Skeletal Muscle Fiber Development