MYT1 Antikörper (pThr495)

Produktnummer ABIN389599

Dieses Kaninchen Polyklonal-Antikörper erkennt spezifisch MYT1 in WB, IHC (p) und DB. Er zeigt eine Reaktivität gegenüber Human und wurde in 1 Publikation erwähnt.

Kurzübersicht für MYT1 Antikörper (pThr495) (ABIN389599)

Target: MYT1 (Myelin Transcription Factor 1 (MYT1))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser MYT1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Dot Blot (DB)

Klon: RB7898

Produktdetails anti-MYT1 Antikörper

Bindungsspezifität: pThr495

Aufreinigung: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogen: This MYT1 Antibody is generated from rabbits immunized with a KLH conjugated synthetic phosphopeptide corresponding to amino acid residues surrounding T495 of human MYT1.

Isotyp: Ig Fraction

Anwendungsinformationen

Applikationshinweise: WB: 1:1000. IHC-P: 1:50~100. DB: 1:500

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Haltbarkeit: 6 months

Referenzen für anti-MYT1 Antikörper (ABIN389599)

Mac?rek, Lindqvist, Lim, Lampson, Klompmaker, Freire, Clouin, Taylor, Yaffe, Medema: "Polo-like kinase-1 is activated by aurora A to promote checkpoint recovery." in: Nature, Vol. 455, Issue 7209, pp. 119-23, (2008) (PubMed).

Details zu MYT1

Target: MYT1 (Myelin Transcription Factor 1 (MYT1))

Andere Bezeichnung: MYT1

Hintergrund: The protein encoded by this gene is a member of the serine/threonine protein kinase family. This kinase preferentially phosphorylates and inactivates cell division cycle 2 protein (CDC2), and thus negatively regulates cell cycle G2/M transition. This kinase is associated with the membrane throughout the cell cycle. Its activity is highly regulated during the cell cycle. Protein kinases AKT1/PKB and PLK (Polo-like kinase) have been shown to phosphorylate and regulate the activity of this kinase. Alternatively spliced transcript variants encoding distinct isoforms have been reported.

Molekulargewicht: 54521

Gen-ID: 9088

NCBI Accession: NP_001245379, NP_001245380, NP_004194, NP_872629

UniProt: Q99640

Pathways: Zellzyklus