beta-2 Microglobulin Antikörper (C-Term)
Kurzübersicht für beta-2 Microglobulin Antikörper (C-Term) (ABIN389259)
Target
Alle beta-2 Microglobulin (B2M) Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
Klon
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Bindungsspezifität
- AA 86-118, C-Term
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Aufreinigung
- This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
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Immunogen
- This B2M antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 86-118 amino acids from the C-terminal region of human B2M.
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Isotyp
- Ig Fraction
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Applikationshinweise
- WB: 1:1000. IHC-P: 1:10~50. FC: 1:10~50
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Buffer
- Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
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Konservierungsmittel
- Sodium azide
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Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Lagerung
- 4 °C,-20 °C
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Informationen zur Lagerung
- Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.
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Haltbarkeit
- 6 months
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: "Overexpression of B2M and loss of ALK7 expression are associated with invasion, metastasis, and poor-prognosis of the pancreatic ductal adenocarcinoma." in: Cancer biomarkers : section A of Disease markers, Vol. 15, Issue 6, pp. 735-43, (2015) (PubMed).
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- beta-2 Microglobulin (B2M) (beta-2-Microglobulin (B2M))
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Andere Bezeichnung
- B2M
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Hintergrund
- Beta-2-microglobulin is a serum protein found in association with the major histocompatibility complex (MHC) class I heavy chain on the surface of nearly all nucleated cells.
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Molekulargewicht
- 13715
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Gen-ID
- 567
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NCBI Accession
- NP_004039
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UniProt
- P61769
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Pathways
- T-Zell Rezeptor Signalweg, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process
Target
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