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beta-2 Microglobulin Antikörper (C-Term)

Name: beta-2 Microglobulin Antikörper (C-Term)
SKU: ABIN389259
Price: 445.5 EUR
Availability: InStock

B2M Reaktivität: Human WB, FACS, IHC (p) Wirt: Kaninchen Polyclonal RB14613 unconjugated

B2M Antibody (C-term) (ABIN389259 and ABIN2839397) western blot analysis in Jurkat cell line lysates (35 μg/lane). (beta-2 Microglobulin Antikörper (C-Term))

B2M Antibody (C-term) (ABIN389259 and ABIN2839397) flow cytometric analysis of Hela cells (right histogram) compared to a negative control cell (left histogram). (beta-2 Microglobulin Antikörper (C-Term))

FACS

Formalin-fixed and paraffin-embedded human lung carcinoma tissue reacted with B2M antibody (C-term) (ABIN389259 and ABIN2839397) , which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. (beta-2 Microglobulin Antikörper (C-Term))

IHC (p)

3 Abbildungen

(1 reference)

Produktnummer ABIN389259

Datenblatt (PDF)

Target Alle beta-2 Microglobulin (B2M) Antikörper anzeigen

beta-2 Microglobulin (B2M) (beta-2-Microglobulin (B2M))
Bindungsspezifität
18

17

15

5

5

5

4

4

2

1

1

1

1

1

1

1
AA 86-118, C-Term
Reaktivität
207

53

31

27

9

4

4

4

3

2

2

1

1

1

1
Human
Wirt
116

116

11

9

1

1
Kaninchen
Passende Sekundärantikörper
Klonalität
138

115

1
Polyklonal
Konjugat
112

33

26

16

13

9

3

3

3

3

3

3

3

3

3

3

3

3

3

1

1

1

1

1

1
Dieser beta-2 Microglobulin Antikörper ist unkonjugiert
Applikation
129

115

74

65

62

42

41

32

27

18

17

15

13

12

6

4

3

2

2

2

2

2

2

1

1

1

1

1

1

1

1

1

1

1

1

1
Western Blotting (WB), Flow Cytometry (FACS), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Aufreinigung

This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.

Immunogen

This B2M antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 86-118 amino acids from the C-terminal region of human B2M.

Klon

RB14613

Isotyp

Ig Fraction

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anti-beta-2-Microglobulin (B2M) antibody (Biotin)
B2M Reaktivität: Human WB, FACS, ELISA, IP, IHC (p), ICC Wirt: Maus Monoclonal B2M-01 Biotin

Applikationshinweise

WB: 1:1000. IHC-P: 1:10~50. FC: 1:10~50

Beschränkungen

Nur für Forschungszwecke einsetzbar
Format

Liquid

Buffer

Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Konservierungsmittel

Sodium azide

Vorsichtsmaßnahmen

This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung

4 °C,-20 °C

Informationen zur Lagerung

Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Haltbarkeit

6 months
Liu, Yang, Li, Liu, Miao, Yang, Zou, Yuan: "Overexpression of B2M and loss of ALK7 expression are associated with invasion, metastasis, and poor-prognosis of the pancreatic ductal adenocarcinoma." in: Cancer biomarkers : section A of Disease markers, Vol. 15, Issue 6, pp. 735-43, (2015) (PubMed).
Target

beta-2 Microglobulin (B2M) (beta-2-Microglobulin (B2M))

Andere Bezeichnung

B2M (B2M Produkte)

Synonyme

Ly-m11 antikoerper, beta2-m antikoerper, beta2m antikoerper, bwm antikoerper, wu:fa94c05 antikoerper, wu:fb10a09 antikoerper, b2m-W01 antikoerper, b2m-W03 antikoerper, b2m-Z01 antikoerper, b2m-Z02 antikoerper, b2m-Z03 antikoerper, B2M antikoerper, b2m antikoerper, B2MG antikoerper, wu:fb66f11 antikoerper, wu:fj01f08 antikoerper, zgc:64161 antikoerper, b-2-m antikoerper, beta-2-microglobulin antikoerper, beta-2 microglobulin antikoerper, beta-2-microglobulin S homeolog antikoerper, beta-2-microglobulin, like antikoerper, B2M antikoerper, B2m antikoerper, b2m antikoerper, b2m.S antikoerper, b2ml antikoerper

Hintergrund

Beta-2-microglobulin is a serum protein found in association with the major histocompatibility complex (MHC) class I heavy chain on the surface of nearly all nucleated cells.

Molekulargewicht

13715

Gen-ID

567

NCBI Accession

NP_004039

UniProt

P61769

Pathways

T-Zell Rezeptor Signalweg, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process