FZD1 Antikörper (C-Term)

Produktnummer ABIN389235

Dieses Anti-FZD1-Antikörper ist ein Kaninchen Polyklonal-Antikörper zur Detektion von FZD1 in WB. Geeignet für Human. Dieses Primary Antibody wurde in 3+ Publikationen zitiert.

Kurzübersicht für FZD1 Antikörper (C-Term) (ABIN389235)

Target: FZD1 (Fzd1) (Frizzled Family Receptor 1 (Fzd1))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser FZD1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Klon: RB14327

Produktdetails anti-FZD1 Antikörper

Bindungsspezifität: AA 504-533, C-Term

Homologie: C, M, Rat, X

Aufreinigung: This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.

Immunogen: This FZD1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 504-533 amino acids from the C-terminal region of human FZD1.

Isotyp: Ig Fraction

Anwendungsinformationen

Applikationshinweise: WB: 1:1000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Haltbarkeit: 6 months

Referenzen für anti-FZD1 Antikörper (ABIN389235)

Yang, Yang, Li, Liu, Zou, Yuan, Xu: "Overexpression of FZD1 and CAIX are Associated with Invasion, Metastasis, and Poor-Prognosis of the Pancreatic Ductal Adenocarcinoma." in: Pathology oncology research : POR, Vol. 24, Issue 4, pp. 899-906, (2018) (PubMed).

Yu, Yerges-Armstrong, Chu, Zmuda, Zhang: "Transcriptional Regulation of Frizzled-1 in Human Osteoblasts by Sp1." in: PLoS ONE, Vol. 11, Issue 10, pp. e0163277, (2017) (PubMed).

Zhang, Kuipers, Yerges-Armstrong, Nestlerode, Jin, Wheeler, Patrick, Bunker, Zmuda: "Functional and association analysis of frizzled 1 (FZD1) promoter haplotypes with femoral neck geometry." in: Bone, Vol. 46, Issue 4, pp. 1131-7, (2010) (PubMed).

Details zu FZD1

Target: FZD1 (Fzd1) (Frizzled Family Receptor 1 (Fzd1))

Andere Bezeichnung: FZD1

Hintergrund: Members of the 'frizzled' proten family are 7-transmembrane domain proteins that are receptors for Wnt signaling proteins. The FZD1 protein contains a signal peptide, a cysteine-rich domain in the N-terminal extracellular region, 7 transmembrane domains, and a C-terminal PDZ domain-binding motif.The FZD1 transcript is expressed in various tissues.

Molekulargewicht: 71158

Gen-ID: 8321

NCBI Accession: NP_003496

UniProt: Q9UP38

Pathways: WNT Signalweg, Asymmetric Protein Localization