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KLF4 Antikörper (AA 69-101)

Dieses Anti-KLF4-Antikörper ist ein Kaninchen Polyklonal-Antikörper zur Detektion von KLF4 in WB, IF und IHC (p). Geeignet für Human. Dieses Primary Antibody wurde in 1 Publikation zitiert.
Produktnummer ABIN389187

Kurzübersicht für KLF4 Antikörper (AA 69-101) (ABIN389187)

Target

Alle KLF4 Antikörper anzeigen
KLF4 (Kruppel-Like Factor 4 (Gut) (KLF4))

Reaktivität

  • 107
  • 35
  • 26
  • 8
  • 7
  • 6
  • 6
  • 6
  • 5
  • 5
  • 2
  • 2
  • 1
  • 1
  • 1
Human

Wirt

  • 93
  • 23
  • 1
Kaninchen

Klonalität

  • 80
  • 37
Polyklonal

Konjugat

  • 87
  • 6
  • 5
  • 5
  • 4
  • 3
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
Dieser KLF4 Antikörper ist unkonjugiert

Applikation

  • 91
  • 55
  • 48
  • 33
  • 29
  • 22
  • 18
  • 9
  • 9
  • 6
  • 2
  • 2
  • 2
  • 1
  • 1
Western Blotting (WB), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Klon

RB14263
  • Bindungsspezifität

    • 12
    • 9
    • 8
    • 8
    • 6
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 69-101

    Aufreinigung

    This antibody is purified through a protein A column, followed by peptide affinity purification.

    Immunogen

    This KLF4 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 69-101 amino acids of human KLF4.

    Isotyp

    IgG
  • Applikationshinweise

    IF: 1:10~50. IF: 1:10~50. WB: 1:2000. IHC-P: 1:10~50. IHC-P: 1:10~50

    Beschränkungen

    Nur für Forschungszwecke einsetzbar
  • Format

    Liquid

    Buffer

    Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

    Konservierungsmittel

    Sodium azide

    Vorsichtsmaßnahmen

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    Lagerung

    4 °C,-20 °C

    Informationen zur Lagerung

    Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.

    Haltbarkeit

    6 months
  • Orlova, Tsai, Baybis, Heuer, Sisodiya, Thom, Strauss, Aronica, Storm, Crino: "Early progenitor cell marker expression distinguishes type II from type I focal cortical dysplasias." in: Journal of neuropathology and experimental neurology, Vol. 69, Issue 8, pp. 850-63, (2010) (PubMed).

  • Target

    KLF4 (Kruppel-Like Factor 4 (Gut) (KLF4))

    Andere Bezeichnung

    KLF4

    Hintergrund

    Transcription factor, can act both as activator and as repressor. Binds the 5'-CACCC-3' core sequence. Binds to the promoter region of its own gene and can activate its own transcription. Regulates the expression of key transcription factors during embryonic development. Plays an important role in maintaining embryonic stem cells, and in preventing their differentiation. Required for establishing the barrier function of the skin and for postnatal maturation and maintenance of the ocular surface. Involved in the differentiation of epithelial cells and may also function in skeletal and kidney development Contributes to the down-regulation of p53/TP53 transcription.

    Molekulargewicht

    54671

    Gen-ID

    9314

    NCBI Accession

    NP_004226

    UniProt

    O43474

    Pathways

    Peptide Hormone Metabolism, Stem Cell Maintenance
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