KLF4 Antikörper (AA 69-101)

Produktnummer ABIN389187

Produktdetails anti-KLF4 Antikörper

Target: KLF4 (Kruppel-Like Factor 4 (Gut) (KLF4))

Bindungsspezifität: AA 69-101

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser KLF4 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Aufreinigung: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogen: This KLF4 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 69-101 amino acids of human KLF4.

Klon: RB14263

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: IF: 1:10~50. IF: 1:10~50. WB: 1:2000. IHC-P: 1:10~50. IHC-P: 1:10~50

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Haltbarkeit: 6 months

Referenzen für anti-KLF4 Antikörper (ABIN389187)

Orlova, Tsai, Baybis, Heuer, Sisodiya, Thom, Strauss, Aronica, Storm, Crino: "Early progenitor cell marker expression distinguishes type II from type I focal cortical dysplasias." in: Journal of neuropathology and experimental neurology, Vol. 69, Issue 8, pp. 850-63, (2010) (PubMed).

Details zu KLF4

Target: KLF4 (Kruppel-Like Factor 4 (Gut) (KLF4))

Andere Bezeichnung: KLF4 (KLF4 Produkte)

Hintergrund: Transcription factor, can act both as activator and as repressor. Binds the 5'-CACCC-3' core sequence. Binds to the promoter region of its own gene and can activate its own transcription. Regulates the expression of key transcription factors during embryonic development. Plays an important role in maintaining embryonic stem cells, and in preventing their differentiation. Required for establishing the barrier function of the skin and for postnatal maturation and maintenance of the ocular surface. Involved in the differentiation of epithelial cells and may also function in skeletal and kidney development Contributes to the down-regulation of p53/TP53 transcription.

Molekulargewicht: 54671

Gen-ID: 9314

NCBI Accession: NP_004226

UniProt: O43474

Pathways: Peptide Hormone Metabolism, Stem Cell Maintenance