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USP8 Antikörper (N-Term)

This anti-USP8 antibody (ABIN388890) is a Rabbit Polyclonal antibody detecting USP8 in WB. Suitable for Human.
Produktnummer ABIN388890

Kurzübersicht für USP8 Antikörper (N-Term) (ABIN388890)

Target

Alle USP8 Antikörper anzeigen
USP8 (Ubiquitin Specific Peptidase 8 (USP8))

Reaktivität

  • 38
  • 4
  • 3
  • 3
  • 3
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
Human

Wirt

  • 34
  • 3
  • 1
Kaninchen

Klonalität

  • 35
  • 3
Polyklonal

Konjugat

  • 28
  • 2
  • 2
  • 2
  • 2
  • 2
Dieser USP8 Antikörper ist unkonjugiert

Applikation

  • 35
  • 16
  • 15
  • 8
  • 7
  • 5
  • 4
  • 2
  • 1
  • 1
  • 1
  • 1
Western Blotting (WB)

Klon

RB4284
  • Bindungsspezifität

    • 7
    • 7
    • 5
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 1-30, N-Term

    Homologie

    M

    Aufreinigung

    This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.

    Immunogen

    This USP8 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 1-30 amino acids from the N-terminal region of human USP8.

    Isotyp

    Ig Fraction
  • Applikationshinweise

    WB: 1:1000

    Beschränkungen

    Nur für Forschungszwecke einsetzbar
  • Format

    Liquid

    Buffer

    Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

    Konservierungsmittel

    Sodium azide

    Vorsichtsmaßnahmen

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    Lagerung

    4 °C,-20 °C

    Informationen zur Lagerung

    Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.

    Haltbarkeit

    6 months
  • Target

    USP8 (Ubiquitin Specific Peptidase 8 (USP8))

    Andere Bezeichnung

    USP8

    Hintergrund

    USP8 is a ubiquitin specific protease that plays an important regulatory role at the level of protein turnover by preventing degradation. USP8 is involved in cell proliferation, and probably regulates the stability of STAM2 and RASGRF1. USP8 may regulate T-cell anergy mediated by RNF128 via the formation of a complex containing RNF128 and STAM2. As revealed by structur/function studies, USP8 forms a ternary complex with RNF128 and OTUB1, and interacts with the SH3 domain of STAM2 and RASGRF1. Expression of USP8 is induced Upon growth stimulation in starved human fibroblasts, and expression decreases in response to growth arrest induced by cell-cell contact.

    Molekulargewicht

    127523

    Gen-ID

    9101

    NCBI Accession

    NP_001122082, NP_001122083, NP_005145

    UniProt

    P40818
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