BMPR1A Antikörper (AA 166-195)

Produktnummer ABIN388735

Dieses Kaninchen Polyklonal-Antikörper erkennt spezifisch BMPR1A in WB und IHC (p). Er zeigt eine Reaktivität gegenüber Human und wurde in 1 Publikation erwähnt.

Kurzübersicht für BMPR1A Antikörper (AA 166-195) (ABIN388735)

Target: BMPR1A (Bone Morphogenetic Protein Receptor 1A (BMPR1A))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser BMPR1A Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Klon: RB05263

Produktdetails anti-BMPR1A Antikörper

Bindungsspezifität: AA 166-195

Aufreinigung: This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.

Immunogen: This BMPR1A antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 166-195 amino acids from the Central region of human BMPR1A.

Isotyp: Ig Fraction

Anwendungsinformationen

Applikationshinweise: WB: 1:2000. WB: 1:1000. IHC-P: 1:50~100

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid freeze-thaw cycles.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots.

Haltbarkeit: 6 months

Referenzen für anti-BMPR1A Antikörper (ABIN388735)

Zhang, Feng, Yang, Koga, Teitelbaum: "The bone morphogenetic protein signaling pathway is upregulated in a mouse model of total parenteral nutrition." in: The Journal of nutrition, Vol. 139, Issue 7, pp. 1315-21, (2009) (PubMed).

Details zu BMPR1A

Target: BMPR1A (Bone Morphogenetic Protein Receptor 1A (BMPR1A))

Andere Bezeichnung: BMPR1A

Hintergrund: The bone morphogenetic protein (BMP) receptors are a family of transmembrane serine/threonine kinases that include the type I receptors BMPR1A and BMPR1B and the type II receptor BMPR2. These receptors are also closely related to the activin receptors, ACVR1 and ACVR2. The ligands of these receptors are members of the TGF-beta superfamily. TGF-betas and activins transduce their signals through the formation of heteromeric complexes with 2 different types of serine (threonine) kinase receptors: type I receptors of about 50-55 kD and type II receptors of about 70-80 kD. Type II receptors bind ligands in the absence of type I receptors, but they require their respective type I receptors for signaling, whereas type I receptors require their respective type II receptors for ligand binding.

Molekulargewicht: 60198

Gen-ID: 657

NCBI Accession: NP_004320

UniProt: P36894

Pathways: Stem Cell Maintenance