Calmodulin 1 Antikörper (C-Term)

Produktnummer ABIN388399

Dieses Kaninchen Polyklonal-Antikörper erkennt spezifisch Calmodulin 1 in WB und IHC (p). Er zeigt eine Reaktivität gegenüber Human, Ratte und Maus und wurde in 1 Publikation erwähnt.

Kurzübersicht für Calmodulin 1 Antikörper (C-Term) (ABIN388399)

Target: Calmodulin 1 (Calm1)

Reaktivität: Human, Ratte, Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser Calmodulin 1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Klon: RB00561

Produktdetails anti-Calmodulin 1 Antikörper

Bindungsspezifität: AA 117-149, C-Term

Homologie: X, B, C, Zf, Rb, Sh

Aufreinigung: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogen: This Calmodulin antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 117-149 amino acids from the C-terminal region of human Calmodulin.

Isotyp: Ig Fraction

Anwendungsinformationen

Applikationshinweise: WB: 1:2000. WB: 1:2000. IHC-P: 1:250

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Haltbarkeit: 6 months

Referenzen für anti-Calmodulin 1 Antikörper (ABIN388399)

Chan, Vuckovic, Sleno, Olsen, Pogoutse, Havugimana, Hewel, Bajaj, Wang, Musteata, Nislow, Emili: "Target identification by chromatographic co-elution: monitoring of drug-protein interactions without immobilization or chemical derivatization." in: Molecular & cellular proteomics : MCP, Vol. 11, Issue 7, pp. M111.016642, (2012) (PubMed).

Details zu Calmodulin 1

Target: Calmodulin 1 (Calm1)

Andere Bezeichnung: Calmodulin

Hintergrund: Calmodulin is the archetype of the family of calcium-modulated proteins of which nearly 20 members have been found. They are identified by their occurrence in the cytosol or on membranes facing the cytosol and by a high affinity for calcium. Calmodulin contains 149 amino acids and has 4 calcium-binding domains. Its functions include roles in growth and the cell cycle as well as in signal transduction and the synthesis and release of neurotransmitters.

Gen-ID: 808

NCBI Accession: NP_001734, NP_005175, NP_008819

UniProt: P62158

Pathways: cAMP Metabolic Process, Myometrial Relaxation and Contraction, G-protein mediated Events, Interaction of EGFR with phospholipase C-gamma, Phototransduction, BCR Signaling