HTRA1 Antikörper (C-Term)

Produktnummer ABIN388128

Dieses Anti-HTRA1-Antikörper ist ein Kaninchen Polyklonal-Antikörper zur Detektion von HTRA1 in WB und IHC (p). Geeignet für Human. Dieses Primary Antibody wurde in 1 Publikation zitiert.

Kurzübersicht für HTRA1 Antikörper (C-Term) (ABIN388128)

Target: HTRA1 (HtrA Serine Peptidase 1 (HTRA1))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser HTRA1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Klon: RB02327

Produktdetails anti-HTRA1 Antikörper

Bindungsspezifität: AA 381-412, C-Term

Homologie: Rat

Aufreinigung: This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.

Immunogen: This HtrA1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 381-412 amino acids from the C-terminal region of human HtrA1.

Isotyp: Ig Fraction

Anwendungsinformationen

Applikationshinweise: WB: 1:1000. IHC-P: 1:50~100

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid freeze-thaw cycles.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots.

Haltbarkeit: 6 months

Referenzen für anti-HTRA1 Antikörper (ABIN388128)

Chamberland, Wang, Jones, Collins-Racie, LaVallie, Huang, Liu, Morris, Flannery, Yang: "Identification of a novel HtrA1-susceptible cleavage site in human aggrecan: evidence for the involvement of HtrA1 in aggrecan proteolysis in vivo." in: The Journal of biological chemistry, Vol. 284, Issue 40, pp. 27352-9, (2009) (PubMed).

Details zu HTRA1

Target: HTRA1 (HtrA Serine Peptidase 1 (HTRA1))

Andere Bezeichnung: HtrA1

Hintergrund: HtrA1 is a member of the trypsin family of serine proteases. This protein is a secreted enzyme that is proposed to regulate the availability of insulin-like growth factors (IGFs) by cleaving IGF-binding proteins. It has also been suggested to be a regulator of cell growth.

Molekulargewicht: 51287

Gen-ID: 5654

NCBI Accession: NP_002766

UniProt: Q92743

Pathways: Growth Factor Binding