HTRA1 Antikörper (N-Term)

Produktnummer ABIN388127

Es gibt 1 Publikation für dieses Produkt. Der Kaninchen Polyklonal anti-HTRA1 Antikörper wird verwendet zum Nachweis von HTRA1 in Proben von Human und Maus. Er wurde validiert für WB, IF und IHC (p).

Kurzübersicht für HTRA1 Antikörper (N-Term) (ABIN388127)

Target: HTRA1 (HtrA Serine Peptidase 1 (HTRA1))

Reaktivität: Human, Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser HTRA1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Klon: RB02326

Produktdetails anti-HTRA1 Antikörper

Bindungsspezifität: AA 116-147, N-Term

Aufreinigung: This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.

Immunogen: This HtrA1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 116-147 amino acids from the N-terminal region of human HtrA1.

Isotyp: Ig Fraction

Anwendungsinformationen

Applikationshinweise: WB: 1:1000. IF: 1:10~50. WB: 1:2000. IHC-P: 1:10~50

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid freeze-thaw cycles.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots.

Haltbarkeit: 6 months

Referenzen für anti-HTRA1 Antikörper (ABIN388127)

Chamberland, Wang, Jones, Collins-Racie, LaVallie, Huang, Liu, Morris, Flannery, Yang: "Identification of a novel HtrA1-susceptible cleavage site in human aggrecan: evidence for the involvement of HtrA1 in aggrecan proteolysis in vivo." in: The Journal of biological chemistry, Vol. 284, Issue 40, pp. 27352-9, (2009) (PubMed).

Details zu HTRA1

Target: HTRA1 (HtrA Serine Peptidase 1 (HTRA1))

Andere Bezeichnung: HtrA1

Hintergrund: HtrA1 a member of the trypsin family of serine proteases. This protein is a secreted enzyme that is proposed to regulate the availability of insulin-like growth factors (IGFs) by cleaving IGF-binding proteins. It has also been suggested to be a regulator of cell growth.

Molekulargewicht: 51287

Gen-ID: 5654

NCBI Accession: NP_002766

UniProt: Q92743

Pathways: Growth Factor Binding