Telefon:
+49 (0)241 95 163 153
Fax:
+49 (0)241 95 163 155
E-Mail:
orders@antikoerper-online.de

JMJD4 Antikörper (N-Term)

JMJD4 Reaktivität: Human WB Wirt: Kaninchen Polyclonal RB10799 unconjugated
Produktnummer ABIN387874
  • Target Alle JMJD4 Produkte
    JMJD4 (Jumonji Domain Containing 4 (JMJD4))
    Bindungsspezifität
    • 8
    • 7
    • 6
    • 3
    • 1
    • 1
    • 1
    AA 1-30, N-Term
    Reaktivität
    • 26
    • 12
    • 5
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    Human
    Wirt
    • 26
    Kaninchen
    Klonalität
    • 26
    Polyklonal
    Konjugat
    • 16
    • 2
    • 2
    • 2
    • 2
    • 2
    Dieser JMJD4 Antikörper ist unkonjugiert
    Applikation
    • 26
    • 15
    • 8
    • 4
    • 3
    • 1
    Western Blotting (WB)
    Aufreinigung
    This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
    Immunogen
    This JMJD4 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 1-30 amino acids from the N-terminal region of human JMJD4.
    Klon
    RB10799
    Isotyp
    Ig Fraction
  • Applikationshinweise
    WB: 1:1000
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Buffer
    Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Lagerung
    4 °C,-20 °C
    Informationen zur Lagerung
    Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.
    Haltbarkeit
    6 months
  • Target
    JMJD4 (Jumonji Domain Containing 4 (JMJD4))
    Andere Bezeichnung
    JMJD4 (JMJD4 Produkte)
    Synonyme
    JMJD4 antikoerper, 6430559I23 antikoerper, RGD1307186 antikoerper, jumonji domain containing 4 antikoerper, jumonji domain containing 4 L homeolog antikoerper, JMJD4 antikoerper, jmjd4.L antikoerper, Jmjd4 antikoerper
    Hintergrund
    Covalent modification of histones plays critical role in regulating chromatin structure and transcription. While most covalent histone modifications are reversible, only recently has it been established that methyl groups are subject to enzymatic removal from histones. A family of novel JmjC domain-containing histone demethylation (JHDM) enzymes have been identified that perform this specific function. Histone demethylation by JHDM proteins requires cofactors Fe(II) and alpha-ketoglutarate. Family members include JHDM1 (demethylating histone 3 at lysine 36), and JHDM2A as well as JMJD2CH3K9 (both of which demethylate histone 3 at lysine 9). Contributions of histone demethylase activity to tumor development, decreases in cell proliferation, and hormone-dependent transcriptional activation have been observed.
    Molekulargewicht
    52493
    Gen-ID
    65094
    NCBI Accession
    NP_001154937, NP_075383
    UniProt
    Q9H9V9
Sie sind hier:
Kundenservice