Transferrin Receptor Antikörper (Biotin)

Produktnummer ABIN380057

Der Ratte-Monoklonal Anti-Transferrin Receptor-Antikörper wurde für IHC und IHC (fro) validiert. Er ist geeignet zum Nachweis von Transferrin Receptor in Proben aus Maus. }

Kurzübersicht für Transferrin Receptor Antikörper (Biotin) (ABIN380057)

Target: Transferrin Receptor (TFRC) (Transferrin Receptor (p90, CD71) (TFRC))

Reaktivität: Maus

Wirt: Ratte

Klonalität: Monoklonal

Konjugat: Dieser Transferrin Receptor Antikörper ist konjugiert mit Biotin

Applikation: Immunohistochemistry (IHC), Immunohistochemistry (Frozen Sections) (IHC (fro))

Klon: ER-MP21

Produktdetails anti-Transferrin Receptor Antikörper (Biotin)

Spezifität: The antigen is a 200  kDa protein (non-reducing conditions) consisting of two identical chains. The recognized epitope of the receptor is not located at the transferrin binding site. Antigen distribution: Differentiation stage-dependent inhibition of macrophage proliferation by ER-MP21 in MCSF-stimulated bone marrow cultures. Macrophage progeny at day 7 in bone marrow cultures, treated in parallel on various days by irradiation (1500 rad 60Co gamma-radiation) or addition of ER-MP21 (30 μg/mL final concentration). Cell numbers were quantified using the MTT assay and expressed relative to untreated controls. Relative growth inhibition calculated from data represented in left figure. For mAbor radiation treated cultures, the number of cell cycles needed to reach the cell number in untreated controls was calculated. Values obtained for irradiated cultures were taken as 100 % inhibition controls and values for ER-MP21 - treated cultures were expressed relative to these. Specificity: Mouse: transfer in receptor. Other species: not tested.

Aufreinigung: Affinity purified

Immunogen: Macrophage precursor cells

Anwendungsinformationen

Applikationshinweise: Approved: IHC, IHC-Fr (1:200)

Usage: The applications listed have been tested for the unconjugated form of this product. Other forms have not been tested.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Rekonstitution: 0.5 mL distilled water

Konzentration: Lot specific

Buffer: Lyophilized from PBS  pH 7.2, 10 mg/mL BSA, 0.1 % sodium azide

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C

Informationen zur Lagerung: Store at 4°C.

Details zu Transferrin Receptor

Target: Transferrin Receptor (TFRC) (Transferrin Receptor (p90, CD71) (TFRC))

Andere Bezeichnung: CD71 / Transferrin Receptor

Hintergrund: Name/Gene ID: TFRC
Subfamily: Metallopeptidase M28B
Family: Protease

Synonyms: TFRC, CD71, TFR1, TRFR, TFR, TR, CD71 antigen, p90, T9, Transferrin receptor, Transferrin receptor protein 1

Gen-ID: 7037

UniProt: P02786

Pathways: Transition Metal Ion Homeostasis