S100A8 Antikörper
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- Target Alle S100A8 Antikörper anzeigen
- S100A8 (S100 Calcium Binding Protein A8 (S100A8))
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Reaktivität
- Human
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Wirt
- Maus
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Klonalität
- Monoklonal
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Konjugat
- Dieser S100A8 Antikörper ist unkonjugiert
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Applikation
- Immunohistochemistry (IHC), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
- Spezifität
- The antigen is MRP8, the epitope is suspected in the central portion of the peptide. Antigen distribution: Isolated cells: The antigen is found in granulocytes and monocytes but not in other blood cells. In cultured monocytes, maximum MRP8 is expressed after 3 - 4 days. Myeloid leukaemia stain positive. Tissue sections: MRP8 is found in a distinct subpopulation of inflammatory perivascular infiltrates of the myelo-monocytic lineage. Macrophages synthesise MRP8 increasingly during the late stages of inflammation. A low MRP8 (and high MRP- 14) expression by macrophages was also reported in granulomatous diseases such as tuberculosis and sarcoidis. In non-granulomatous chronic inflammatory diseases such as chronic rheumatoid arthritis or chronic rejection after allograft transplantation, MRP8 and MRP14 positive cells consist of different subpopulations. Specificity: Human: MRP8 in stimulated monocytes and macrophages in late phase or chronic inflammation. Other: The antibody reacts with bovine spleen but does not react with rat tissues. It shows a diffuse reaction with swine spleen.
- Aufreinigung
- Affinity purified
- Immunogen
- Cultured human monocytes
- Klon
- 8-5C2
- Top Product
- Discover our top product S100A8 Primärantikörper
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- Applikationshinweise
- Optimal working dilution should be determined by the investigator.
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Lyophilized
- Rekonstitution
- 0.5 mL distilled water
- Konzentration
- Lot specific
- Buffer
- Lyophilized from PBS pH 7.2, 5 mg/mL BSA, 0.09 % sodium azide
- Konservierungsmittel
- Sodium azide
- Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Lagerung
- 4 °C
- Informationen zur Lagerung
- Store at 4°C.
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- Target
- S100A8 (S100 Calcium Binding Protein A8 (S100A8))
- Andere Bezeichnung
- S100A8 / MRP8 (S100A8 Produkte)
- Synonyme
- 60B8AG antikoerper, CAGA antikoerper, CFAG antikoerper, CGLA antikoerper, CP-10 antikoerper, L1Ag antikoerper, MA387 antikoerper, MIF antikoerper, MRP8 antikoerper, NIF antikoerper, P8 antikoerper, Mrp8 antikoerper, S100A8 antikoerper, 60B8Ag antikoerper, AI323541 antikoerper, B8Ag antikoerper, CFAg antikoerper, Caga antikoerper, p8 antikoerper, MRP-8 antikoerper, S100 calcium binding protein A8 antikoerper, S100 calcium binding protein A8 (calgranulin A) antikoerper, S100A8 antikoerper, S100a8 antikoerper
- Hintergrund
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Name/Gene ID: S100A8
Synonyms: S100A8, 60B8AG, CFAG, CAGA, Calgranulin A, Calgranulin-A, Calprotectin L1L subunit, Cystic fibrosis antigen, CGLA, L1Ag, NIF, p8, Protein S100-A8, MRP8, Urinary stone protein band A, CP-10, MA387, MRP-8 - Gen-ID
- 6279
- UniProt
- P05109
- Pathways
- Transition Metal Ion Homeostasis, Positive Regulation of Endopeptidase Activity, S100 Proteine
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