ITGA2 Antikörper

Produktnummer ABIN376997

Der Maus Monoklonal Anti-ITGA2-Antikörper wurde für FACS validiert. Er ist geeignet, ITGA2 in Proben von Human zu detektieren.

Kurzübersicht für ITGA2 Antikörper (ABIN376997)

Target: ITGA2 (Integrin alpha 2 (ITGA2))

Reaktivität: Human

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser ITGA2 Antikörper ist unkonjugiert

Applikation: Flow Cytometry (FACS)

Klon: HAS-4

Produktdetails anti-ITGA2 Antikörper

Spezifität: Human CD49b, Mr 160 kDa

Produktmerkmale: Mouse Anti-Human CD49b-UNLB

Aufreinigung: Purified

Immunogen: Human keratinocytes

Isotyp: IgG2a

Anwendungsinformationen

Applikationshinweise:

• Applications: FC - Quality tested , IHC-FS - Reported in literature , ICC - Reported in literature , IP - Reported in literature , Block - Reported in literature
• Working Dilutions: Flow Cytometry Purified (UNLB) antibody 1 g/106 cells FITC and PE conjugates 10 L/106 cells For flow cytometry, the suggested use of these reagents is in a final volume of 100 L

Probenmenge: 1 mL

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 0.1 mg/mL

Buffer: 0.1 mg of purified immunoglobulin in 1.0 mL of borate buffered saline,  pH 8.2. No preservatives or amine-containing buffer salts added

Konservierungsmittel: Without preservative

Handhabung: Each reagent is stable for the period shown on the bottle label if stored as directed.

Lagerung: 4 °C

Informationen zur Lagerung: Store at 2-8°C

Details zu ITGA2

Target: ITGA2 (Integrin alpha 2 (ITGA2))

Andere Bezeichnung: CD49b

Hintergrund: CD49b, a member of the integrin family of extracellular matrix and cell adhesion molecules, is the integrin α 2 chain. CD49b associates noncovalently with CD29, the integrin β 1 subunit, to form the heterodimer integrin a2b1 that binds laminin and collagen. It is expressed on B and T lymphocytes, NK cells, monocytes, platelets, fibroblasts and long-term cultured T cells. CD49b/CD29 mediates the Mg ++ - dependent adhesion of platelets to collagen. It may also be utilized by fibroblasts for the reorganization of the collagen matrix during would healing.

Pathways: CXCR4-mediated Signaling Events, Smooth Muscle Cell Migration, Integrin Complex