CD33 Antikörper

Produktnummer ABIN376397

Der Maus Monoklonal anti-CD33 Antikörper wird verwendet zum Nachweis von CD33 in Proben von Human. Er wurde validiert für FACS, WB, IP, IHC (fro), ICC und BR.

Kurzübersicht für CD33 Antikörper (ABIN376397)

Target: CD33

Reaktivität: Human

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser CD33 Antikörper ist unkonjugiert

Applikation: Flow Cytometry (FACS), Western Blotting (WB), Immunoprecipitation (IP), Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunocytochemistry (ICC), Blocking Reagent (BR)

Klon: WM53

Produktdetails anti-CD33 Antikörper

Verwendungszweck: Mouse Anti-Human CD33-LE/AF

Spezifität: Human CD33, Mr 67 kDa

Produktmerkmale: Low Endotoxin/Azide Free Anti-Human CD33 antibody for use in flow cytometry, immunohistochemistry / immunocytochemistry, western blotting, immunoprecipitation, and blocking assays.

Endotoxin-Niveau: Low Endotoxin

Isotyp: IgG1

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 0.5 mg/mL

Buffer: Phosphate buffered saline, pH 7.4

Konservierungsmittel: Azide free

Handhabung: Each reagent is stable for the period shown on the bottle label if stored as directed.

Lagerung: 4 °C

Informationen zur Lagerung: 2-8°C

Details zu CD33

Target: CD33

Andere Bezeichnung: CD33

Hintergrund: CD33 is a 67 kDa type I transmembrane glycoprotein and a member of the sialoadhesin family of cell surface receptors. It is absent from pluripotent stem cells but appears on myelomonocytic precursors after CD34. It then continues to be expressed on both the myeloid and monocyte lineages, although it is absent on granulocytes. While it has been reported that CD33 can function as a sialic acid-dependent cell adhesion molecule, cells expressing CD33 require desialylation before they can bind cells bearing the appropriate sialoglycoconjugates. This suggests that inhibitory cis interactions may regulate or block any adhesion function.

Gen-ID: 945

UniProt: P20138