Der Hamster Monoklonal anti-CD79b Antikörper (Klon HM79-12) (ABIN376383) detektiert spezifisch CD79b in WB, FACS und IP.
Dieser Antikörper reagiert spezifisch mit Proben aus Maus.
Murine CD79 is a 23/21 kDa disulfide-linked heterodimer composed of an α chain (CD79a/mb-1) and a β chain (CD79b/B29) that associates non-covalently with membrane immunoglobulin (Ig) to form the B cell receptor (BCR) complex. Its expression is restricted to B lymphocytes, first appearing on the surface at the pro-B cell stage prior to productive Ig gene rearrangements and remaining through all stages of B-cell differentiation prior to plasma cells. It has been proposed that the CD79 complex on pro-B cell surfaces may function to induce early B-cell differentiation.