CD24 Antikörper

Produktnummer ABIN376382

Der Ratte Monoklonal anti-CD24 Antikörper wird verwendet zum Nachweis von CD24 in Proben von Maus. Er wurde validiert für FACS.

Kurzübersicht für CD24 Antikörper (ABIN376382)

Target: CD24 (CD24 Molecule (CD24))

Reaktivität: Maus

Wirt: Ratte

Klonalität: Monoklonal

Konjugat: Dieser CD24 Antikörper ist unkonjugiert

Applikation: Flow Cytometry (FACS)

Klon: 30-F1

Produktdetails anti-CD24 Antikörper

Verwendungszweck: Rat Anti-Mouse CD24-LE/AF

Spezifität: Mouse CD24, Mr 35-45 kDa

Produktmerkmale: Low Endotoxin/Azide Free Anti-Mouse CD24 antibody for use in flow cytometry assays.

Endotoxin-Niveau: Low Endotoxin

Immunogen: Mouse thymus or spleen

Isotyp: IgG2c

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 0.5 mg/mL

Buffer: Phosphate buffered saline, pH 7.4

Konservierungsmittel: Azide free

Handhabung: Each reagent is stable for the period shown on the bottle label if stored as directed.

Lagerung: 4 °C

Informationen zur Lagerung: 2-8°C

Details zu CD24

Target: CD24 (CD24 Molecule (CD24))

Andere Bezeichnung: CD24

Hintergrund: CD24 is expressed in B cells until their terminal differentiation into plasma cells. It has been used widely as a marker to fractionate different B-lineage differentiation stages. CD24 has been found on a variety of other hematopoietic and neural cell types, and is now classified as a costimulatory molecule. The CD24/HSA molecule is composed mostly of carbohydrate, with a protein core of only 31-35 AA in the human and 27 AA in the mouse. The molecular mass is variable, ranging from 38-70 kDa. CD24 is now included in the large group of phosphatidylinositol-anchored membrane proteins. Studies with purified CD24 applied to latex beads have demonstrated a self-binding property, suggesting that the molecule is capable of promoting homotypic aggregation, binding and cell adhesion. This is supported by earlier observations of the blockade of B cell lymphoblast aggregation with anti-CD24 monoclonal antibody. Recent studies of murine CD24 have assigned a role for CD24/HSA as a ligand for P-selectin, a calcium-dependent lectin.

Gen-ID: 12484

UniProt: P24807

Pathways: Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Activated T Cell Proliferation