CD38 Antikörper (APC)

Produktnummer ABIN375787

Dieses Ratte Monoklonal-Antikörper erkennt spezifisch CD38 in FACS. Er zeigt eine Reaktivität gegenüber Maus.

Kurzübersicht für CD38 Antikörper (APC) (ABIN375787)

Target: CD38

Reaktivität: Maus

Wirt: Ratte

Klonalität: Monoklonal

Konjugat: Dieser CD38 Antikörper ist konjugiert mit APC

Applikation: Flow Cytometry (FACS)

Klon: NIMR-5

Produktdetails anti-CD38 Antikörper (APC)

Spezifität: Mouse CD38, Mr 42 kDa

Produktmerkmale: Rat Anti-Mouse CD38-APC

Aufreinigung: Purified

Immunogen: BCL1 plasma membrane glycoproteins

Isotyp: IgG2a

Anwendungsinformationen

Applikationshinweise:

• Applications: FC - Quality tested , IHC-FS - Reported in literature , IP - Reported in literature , ELISA - Reported in literature , Sep - Reported in literature , Activ - Reported in literature , Costim - Reported in literature , Stim - Reported in literature , Apop - Reported in literature , Drug Delivery - Reported in literature , Block - Reported in literature
• Working Dilutions: Flow Cytometry FITC and BIOT conjugates 1 g/106 cells PE, APC, and SPRD conjugates 0.2 g/106 cells For flow cytometry, the suggested use of these reagents is in a final volume of 100 L

Kommentare:

Induction of B lymphocyte proliferation

Probenmenge: 1 mL

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 0.1 mg/mL

Buffer: 0.1 mg in 1.0 mL of PBS/Sodium azide and a stabilizing agent

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Do not freeze!
Protect conjugated products from light.
Each reagent is stable for the period shown on the bottle label if stored as directed.

Lagerung: 4 °C

Informationen zur Lagerung: Store at 2-8°C

Details zu CD38

Target: CD38

Hintergrund: Murine CD38, a type II transmembrane glycoprotein, is a bifunctional ectoenzyme capable of catabolizing nicotinamide adenine dinucleotide (NAD+) to cyclic ADP-ribose (cADPR), and then hydrolyzing cADPR to adenosine diphosphoribose (ADPR). It is expressed at high levels on the surface of peripheral B-lineage cells, and at low density on germinal center B cells from unimmunized mice. It has also been reported to be expressed at moderate levels on NK cells, a proportion of peripheral T cells, and a subpopulation of thymocytes which are mostly TCR αβ +, CD4 -, CD8 -. Murine CD38 is also expressed by all Mac-1 + macrophages in the peritoneal cavities of unimmunized mice, but not by unstimulated bone-marrow-derived macrophages.