ITGAL Antikörper

Produktnummer ABIN375486

Dieses Anti-ITGAL-Antikörper ist ein Maus Monoklonal-Antikörper zur Detektion von ITGAL in FACS, IP und IHC. Geeignet für Human. Dieses Primary Antibody wurde in 1 Publikation zitiert.

Kurzübersicht für ITGAL Antikörper (ABIN375486)

Target: ITGAL (Integrin alpha-L (ITGAL))

Reaktivität: Human

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser ITGAL Antikörper ist unkonjugiert

Applikation: Flow Cytometry (FACS), Immunoprecipitation (IP), Immunohistochemistry (IHC)

Klon: 38

Produktdetails anti-ITGAL Antikörper

Produktmerkmale: The antibody detects: Human CD11a (LFA-1 α )
To insure lot to lot consistency, each batch of product is tested by flow cytometry to conform with the characteristics of a standard reference reagent.

Aufreinigung: Purified

Endotoxin-Niveau: Low Endotoxin

Isotyp: IgG2a

Anwendungsinformationen

Applikationshinweise: Working Dilution:
<= 1 µg/10^6 cells
Representative data are included in this product insert.

Each laboratory should determine an optimum working titer for use in its particular application. Other applications have not been tested but use in such assays should not necessarily be excluded.

Kommentare:

Blocking studies, cell adhesion, cytotoxicity

Probenmenge: 1 mL

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konservierungsmittel: Azide free

Handhabung: Each reagent is stable for the period shown on the bottle label if stored as directed.

Lagerung: -20 °C

Informationen zur Lagerung: Aliquot and freeze the low endotoxin, azide-free product at -20 °C immediately upon receipt.

Referenzen für anti-ITGAL Antikörper (ABIN375486)

Venet, Ribeiro, Décembre, Bellomo, Joshi, Nuovo, Villard, Cluet, Perret, Pescamona, Paidassi, Walzer, Allatif, Belot, Trouillet-Assant, Ricci, Dreux: "Severe COVID-19 patients have impaired plasmacytoid dendritic cell-mediated control of SARS-CoV-2." in: Nature communications, Vol. 14, Issue 1, pp. 694, (2023) (PubMed).

Details zu ITGAL

Target: ITGAL (Integrin alpha-L (ITGAL))

Andere Bezeichnung: CD11a/LFA-1a

Hintergrund: CD11a, also known as leukocyte function-associated antigen-1 (LFA-1 α ), represents the 180 kDa integrin α L subunit which combines with the CD18 β 2 integrin subunit to form the α L β 2 integrin heterodimer. It is expressed on lymphocytes, granulocytes, monocytes, and macrophages and is upregulated on activated T cells. CD11a/LFA-1 α mediates adhesion of lymphocytes to vascular endothelium and is involved in costimulation.

Pathways: Activated T Cell Proliferation, Integrin Complex