EPH Receptor B2 Antikörper (Internal Region)

Produktnummer ABIN375195

Produktdetails anti-EPH Receptor B2 Antikörper

Target: EPH Receptor B2 (EPHB2)

Bindungsspezifität: Internal Region

Reaktivität: Human

Wirt: Ziege

Klonalität: Polyklonal

Konjugat: Dieser EPH Receptor B2 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Enzyme Immunoassay (EIA)

Spezifität: This antibody reacts to EPHB2.

Kreuzreaktivität (Details): Species reactivity (expected):Mouse, Rat, Canine.
Species reactivity (tested):Human.

Aufreinigung: ammonium sulphate precipitation followed by antigen affinity chromatography

Immunogen: Peptide with sequence C-QKDRNHRPKFGQ, from the internal region of the protein sequence

Anwendungsinformationen

Applikationshinweise: ELISA: 1/4000. Western Blot: 1 - 3 μg/mL.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 0.5 mg/mL

Buffer: Tris saline, 0.02 % sodium azide, pH 7.3 with 0.5 % bovine serum albumin

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freezing and thawing.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Details zu EPH Receptor B2

Target: EPH Receptor B2 (EPHB2)

Andere Bezeichnung: EPHB2 (EPHB2 Produkte)

Synonyme: CAPB antikoerper, DRT antikoerper, EK5 antikoerper, EPHT3 antikoerper, ERK antikoerper, Hek5 antikoerper, PCBC antikoerper, Tyro5 antikoerper, ERK2 antikoerper, ERT1 antikoerper, MAPK2 antikoerper, P42MAPK antikoerper, PRKM1 antikoerper, PRKM2 antikoerper, p38 antikoerper, p40 antikoerper, p41 antikoerper, p41mapk antikoerper, RGD1564232 antikoerper, Cek5 antikoerper, Drt antikoerper, ETECK antikoerper, Erk antikoerper, Nuk antikoerper, Prkm5 antikoerper, Qek5 antikoerper, Sek3 antikoerper, cek5 antikoerper, ephb2 antikoerper, xEphB2 antikoerper, si:ch73-160e9.1 antikoerper, tpx2 antikoerper, wu:fb09e10 antikoerper, wu:fc64a03 antikoerper, wu:fi18g12 antikoerper, zgc:112296 antikoerper, EPH receptor B2 antikoerper, mitogen-activated protein kinase 1 antikoerper, Eph receptor B2 antikoerper, EPH receptor B2 L homeolog antikoerper, eph receptor B2a antikoerper, eph receptor B2b antikoerper, EPHB2 antikoerper, MAPK1 antikoerper, Ephb2 antikoerper, ephb2.L antikoerper, ephb2a antikoerper, ephb2b antikoerper

Hintergrund: Protein kinases are enzymes that transfer a phosphate group from a phosphate donor, generally the g phosphate of ATP, onto an acceptor amino acid in a substrate protein. By this basic mechanism, protein kinases mediate most of the signal transduction in eukaryotic cells, regulating cellular metabolism, transcription, cell cycle progression, cytoskeletal rearrangement and cell movement, apoptosis, and differentiation. With more than 500 gene products, the protein kinase family is one of the largest families of proteins in eukaryotes. The family has been classified in 8 major groups based on sequence comparison of their tyrosine (PTK) or serine/threonine (STK) kinase catalytic domains. The tyrosine kinase (TK) group is mainly involved in the regulation of cell-cell interactions such as differentiation, adhesion, motility and death. There are currently about 90 TK genes sequenced, 58 are of receptor protein TK (e.g. EGFR, EPH, FGFR, PDGFR, TRK, and VEGFR families), and 32 of cytosolic TK (e.g. ABL, FAK, JAK, and SRC families).Synonyms: DRT, DRT, EPHT3, EPTH3, ERK, Ephrin type-B receptor 2, HEK5, NY-REN-47, Receptor protein-tyrosine kinase HEK5, Renal carcinoma antigen NY-REN-47, TYRO5, Tyrosine-protein kinase TYRO5, Tyrosine-protein kinase receptor EPH-3

Gen-ID: 2048

NCBI Accession: NP_004433

UniProt: P29323

Pathways: RTK Signalweg, Regulation of long-term Neuronal Synaptic Plasticity, S100 Proteine