AADAT Antikörper (Internal Region)

Produktnummer ABIN375162

Produktdetails anti-AADAT Antikörper

Target: AADAT (Aminoadipate Aminotransferase (AADAT))

Bindungsspezifität: Internal Region

Reaktivität: Human

Wirt: Ziege

Klonalität: Polyklonal

Konjugat: Dieser AADAT Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Enzyme Immunoassay (EIA)

Spezifität: This antibody reacts to AADAT.

Aufreinigung: Affinity chromatography

Immunogen: Peptide with sequence C-KPEDAKNPQKNTPK, from the internal region of the protein sequence

Anwendungsinformationen

Applikationshinweise: Peptide ELISA: 1/32000. Western Blot: 1 - 3 μg/mL.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 0,5 mg/mL

Buffer: Tris saline, 0.02 % sodium azide, pH 7.3 with 0.5 % bovine serum albumin

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freezing and thawing.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Details zu AADAT

Target: AADAT (Aminoadipate Aminotransferase (AADAT))

Andere Bezeichnung: AADAT (AADAT Produkte)

Synonyme: KAT2 antikoerper, KATII antikoerper, AI875679 antikoerper, Aadt antikoerper, Kat2 antikoerper, mKat-2 antikoerper, MGC80030 antikoerper, kat2 antikoerper, katii antikoerper, aminoadipate aminotransferase antikoerper, aminoadipate aminotransferase S homeolog antikoerper, AADAT antikoerper, Aadat antikoerper, aadat.S antikoerper, aadat antikoerper

Hintergrund: Aminoadipate aminotransferase (AADAT) is a protein that is highly similar to mouse and rat kynurenine aminotransferase II. The rat protein is a homodimer with two transaminase activities. One activity is the transamination of alpha-aminoadipic acid, a final step in the saccaropine pathway which is the major pathway for L-lysine catabolism. The other activity involves the transamination of kynurenine to produce kynurenine acid, the precursor of kynurenic acid which has neuroprotective properties. Two alternative transcripts encoding the same isoform have been identified, however, additional alternative transcripts and isoforms may exist. Kynurenine aminotransferase catalyzes the irreversible transamination of the L-tryptophan metabolite L-kynurenine to form kynurenic acid. Kynurenic acid is an antagonist at the glycine site of NMDA receptors and increased levels of kynurenic acid are thought to exert a neuroprotective action in some pathological conditions.Synonyms: 2-aminoadipate aminotransferase, 2-aminoadipate transaminase, Alpha-aminoadipate aminotransferase, KAT2, Kynurenine aminotransferase II, Kynurenine-oxoglutarate aminotransferase II, Kynurenine-oxoglutarate transaminase II

Gen-ID: 51166, 9606

UniProt: Q8N5Z0