IDE Antikörper (Internal Region)

Produktnummer ABIN375106

Dieser Ziege Polyklonal Antikörper detektiert spezifisch IDE in WB. Es zeigt Reaktivität gegenüber Proben von Human und Hund.

Kurzübersicht für IDE Antikörper (Internal Region) (ABIN375106)

Target: IDE (Insulin-Degrading Enzyme (IDE))

Reaktivität: Human, Hund

Wirt: Ziege

Klonalität: Polyklonal

Konjugat: Dieser IDE Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktdetails anti-IDE Antikörper

Bindungsspezifität: Internal Region

Spezifität: This antibody reacts to Insulysin / Insulinase.

Kreuzreaktivität (Details): Species reactivity (expected):Canine.
Species reactivity (tested):Human.

Aufreinigung: Affinity chromatography

Immunogen: Peptide with sequence C-QQYNFDRDNTE, from the internal region of the protein sequence

Anwendungsinformationen

Applikationshinweise: Peptide ELISA: 1/32000. Western Blot: 0.1 - 0.3 μg/mL.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 0,5 mg/mL

Buffer: Tris saline, 0.02 % sodium azide, pH 7.3 with 0.5 % bovine serum albumin

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freezing and thawing.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Details zu IDE

Target: IDE (Insulin-Degrading Enzyme (IDE))

Andere Bezeichnung: Insulin-Degrading Enzyme

Hintergrund: Insulin degrading enzyme (IDE) has a preferential affinity for insulin such that the presence of insulin will inhibit IDE mediated degradation of other substrates. IDE degrades a variety of other peptides including atrial natriuretic peptide and amylin. IDE catabolizes A beta and has been implicated as a candidate enzyme responsible for the degradation and clearance of A beta in the brain. IDE has also been shown to degrade the APP intracellular domain (AICD), a product of gamma secretase cleaved APP that may function in nuclear signaling.Synonyms: Abeta-degrading protease, EC=3.4.24.56, IDE, Insulin protease, Insulinase, Insulysin

Gen-ID: 3416, 9606

UniProt: P14735

Pathways: SARS-CoV-2 Protein Interaktom