ERP29 Antikörper (C-Term)

Produktnummer ABIN375036

Dieses Anti-ERP29-Antikörper ist ein Ziege Polyklonal-Antikörper zur Detektion von ERP29 in WB. Geeignet für Human, Ratte, Maus, Hund, Rind (Kuh) und Schwein.

Kurzübersicht für ERP29 Antikörper (C-Term) (ABIN375036)

Target: ERP29 (Endoplasmic Reticulum Protein 29 (ERP29))

Reaktivität: Human, Ratte, Maus, Hund, Rind (Kuh), Schwein

Wirt: Ziege

Klonalität: Polyklonal

Konjugat: Dieser ERP29 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktdetails anti-ERP29 Antikörper

Bindungsspezifität: C-Term

Spezifität: This antibody reacts to ERP29.

Kreuzreaktivität (Details): Species reactivity (expected):Mouse, Rat, Canine, Bovine, Porcine.
Species reactivity (tested):Human.

Aufreinigung: Affinity chromatography

Immunogen: Peptide with sequence C-EKNKMSDGKKEELQ, from the C-Terminus of the protein sequence

Anwendungsinformationen

Applikationshinweise: Peptide ELISA: 1/2000. Western Blot: 0.1 - 0.3 μg/mL.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 0,5 mg/mL

Buffer: Tris saline, 0.02 % sodium azide, pH 7.3 with 0.5 % bovine serum albumin

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freezing and thawing.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Details zu ERP29

Target: ERP29 (Endoplasmic Reticulum Protein 29 (ERP29))

Andere Bezeichnung: ERP29

Hintergrund: Proper protein folding and post-translational modifications are essential for secretory protein export out of the endoplasmic reticulum. This task is accomplished by chaperone proteins such as protein disulfide isomerase (PDI), GRP94, and BiP. A recently characterized protein, designated ERp29, is closely related to these chaperone proteins and appears to be upregulated during ER stress conditions. ERp29 is a soluble 259-residue protein that is localized to the lumen of the endoplasmic reticulum in all mammalian cells. Research has shown that there are two primary domains within ERp29. The first is the C-terminal region that is a novel, all helical, fold that is most likely involved with ERp29 retention to the ER. The second is the N-terminal region that resembles that of PDI's thioredoxin module. The protein shows sequence similarity to the protein disulfide isomerase family. However, it lacks the thioredoxin motif characteristic of this family, suggesting that this protein does not function as a disulfide isomerase. The protein dimerizes and is thought to play a role in the processing of secretory proteins within the ER.Synonyms: C12orf8, ERp28, ERp31, Endoplasmic reticulum protein ERp29

Gen-ID: 10961

NCBI Accession: NP_006808

UniProt: P30040