KPNA6 Antikörper (Internal Region)

Produktnummer ABIN374979

Produktdetails anti-KPNA6 Antikörper

Target: KPNA6 (Karyopherin alpha 6 (Importin alpha 7) (KPNA6))

Bindungsspezifität: Internal Region

Reaktivität: Human, Maus, Ratte, Rind (Kuh)

Wirt: Ziege

Klonalität: Polyklonal

Konjugat: Dieser KPNA6 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)

Spezifität: This antibody detects KPNA6.

Kreuzreaktivität (Details): Species reactivity (expected):Mouse, Rat, Dog, Pig, Bovine.
Species reactivity (tested):Human.

Aufreinigung: Affinity Chromatography.

Immunogen: Peptide with sequence C-STTGESVITREMVE, from the internal of the protein sequence

Anwendungsinformationen

Applikationshinweise: Peptide ELISA: 1/128000. Western Blot: 0.1 - 0.3 μg/mL.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 0.5 mg/mL

Buffer: Tris saline, pH ~7.3, 0.02 % Sodium Azide, 0.5 % BSA

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freezing and thawing.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Details zu KPNA6

Target: KPNA6 (Karyopherin alpha 6 (Importin alpha 7) (KPNA6))

Andere Bezeichnung: KPNA6 / Importin alpha-7 (KPNA6 Produkte)

Synonyme: IPOA7 antikoerper, Kpna5 antikoerper, NPI-2 antikoerper, KPNA7 antikoerper, karyopherin subunit alpha 6 antikoerper, karyopherin (importin) alpha 6 antikoerper, karyopherin alpha 6 (importin alpha 7) antikoerper, karyopherin alpha 6 (importin alpha 7) S homeolog antikoerper, KPNA6 antikoerper, Kpna6 antikoerper, kpna6.S antikoerper

Hintergrund: Nucleocytoplasmic transport, a signal and energy dependent process, takes place through nuclear pore complexes embedded in the nuclear envelope. The import of proteins containing a nuclear localization signal (NLS) requires the NLS import receptor, a heterodimer of importin alpha and beta subunits also known as karyopherins. Importin alpha binds the NLS containing cargo in the cytoplasm and importin beta docks the complex at the cytoplasmic side of the nuclear pore complex. In the presence of nucleoside triphosphates and the small GTP binding protein Ran, the complex moves into the nuclear pore complex and the importin subunits dissociate. Importin alpha enters the nucleoplasm with its passenger protein and importin beta remains at the pore. The protein encoded by this gene is a member of the importin alpha family.Synonyms: IPOA7, KPNA6, Karyopherin subunit alpha-6

Gen-ID: 23633

NCBI Accession: NP_036448

UniProt: O60684

Pathways: Protein targeting to Nucleus