IGFBP6 Antikörper (Internal Region)

Produktnummer ABIN374965

Dieser Ziege Polyklonal Antikörper detektiert spezifisch IGFBP6 in WB. Es zeigt Reaktivität gegenüber Proben von Human und Rind (Kuh).

Kurzübersicht für IGFBP6 Antikörper (Internal Region) (ABIN374965)

Target: IGFBP6 (Insulin-Like Growth Factor Binding Protein 6 (IGFBP6))

Reaktivität: Human, Rind (Kuh)

Wirt: Ziege

Klonalität: Polyklonal

Konjugat: Dieser IGFBP6 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktdetails anti-IGFBP6 Antikörper

Bindungsspezifität: Internal Region

Spezifität: This antibody reacts to IGFBP6.

Kreuzreaktivität (Details): Species reactivity (expected):Bovine.
Species reactivity (tested):Human.

Aufreinigung: Affinity chromatography

Immunogen: Peptide with sequence C-RPQDVNRRDQQRNP, from the internal region of the protein sequence

Anwendungsinformationen

Applikationshinweise: Peptide ELISA: 1/32000. Western Blot: 0.5 - 1.5 μg/mL.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 0,5 mg/mL

Buffer: Tris saline, 0.02 % sodium azide, pH 7.3 with 0.5 % bovine serum albumin

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freezing and thawing.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Details zu IGFBP6

Target: IGFBP6 (Insulin-Like Growth Factor Binding Protein 6 (IGFBP6))

Andere Bezeichnung: IGFBP6

Hintergrund: IGFBP6 (IGF binding protein 6) is a member of the IGFBP family that regulates the actions of IGFs. It acts extracellularly in an autocrine/paracrine manner. IGFBP6 binds preferentially to IGF-II. IGFBP6 has been shown to inhibit the growth of tumour cells and to promote apotosis. IGFBP6 has been shown to be imported into the nuclei of rhabdomyosarcoma and HEK-293 cells. This is mediated by a NLS sequence that bears limited homology to those found in IGFBP-3 and -5. Deletion of the NLS segment abolishes the pro-apoptotic effect of IGFBP6.Synonyms: IBP-6, IBP6, IGF-binding protein 6, IGFBP-6, Insulin-like growth factor-binding protein 6

Gen-ID: 3489, 9606

UniProt: P24592

Pathways: WNT Signalweg, Myometrial Relaxation and Contraction