IGFBP6 Antikörper (Internal Region)

Produktnummer ABIN374965

Produktdetails anti-IGFBP6 Antikörper

Target: IGFBP6 (Insulin-Like Growth Factor Binding Protein 6 (IGFBP6))

Bindungsspezifität: Internal Region

Reaktivität: Human, Rind (Kuh)

Wirt: Ziege

Klonalität: Polyklonal

Konjugat: Dieser IGFBP6 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Spezifität: This antibody reacts to IGFBP6.

Kreuzreaktivität (Details): Species reactivity (expected):Bovine.
Species reactivity (tested):Human.

Aufreinigung: Affinity chromatography

Immunogen: Peptide with sequence C-RPQDVNRRDQQRNP, from the internal region of the protein sequence

Anwendungsinformationen

Applikationshinweise: Peptide ELISA: 1/32000. Western Blot: 0.5 - 1.5 μg/mL.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 0,5 mg/mL

Buffer: Tris saline, 0.02 % sodium azide, pH 7.3 with 0.5 % bovine serum albumin

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freezing and thawing.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Details zu IGFBP6

Target: IGFBP6 (Insulin-Like Growth Factor Binding Protein 6 (IGFBP6))

Andere Bezeichnung: IGFBP6 (IGFBP6 Produkte)

Synonyme: IBP6 antikoerper, IGFBP-6 antikoerper, IGF-BP6 antikoerper, RBP6A antikoerper, IGFBP6 antikoerper, igfbp6 antikoerper, insulin like growth factor binding protein 6 antikoerper, insulin-like growth factor binding protein 6 antikoerper, IGFBP6 antikoerper, Igfbp6 antikoerper, IGFBP-6 antikoerper, igfbp6 antikoerper

Hintergrund: IGFBP6 (IGF binding protein 6) is a member of the IGFBP family that regulates the actions of IGFs. It acts extracellularly in an autocrine/paracrine manner. IGFBP6 binds preferentially to IGF-II. IGFBP6 has been shown to inhibit the growth of tumour cells and to promote apotosis. IGFBP6 has been shown to be imported into the nuclei of rhabdomyosarcoma and HEK-293 cells. This is mediated by a NLS sequence that bears limited homology to those found in IGFBP-3 and -5. Deletion of the NLS segment abolishes the pro-apoptotic effect of IGFBP6.Synonyms: IBP-6, IBP6, IGF-binding protein 6, IGFBP-6, Insulin-like growth factor-binding protein 6

Gen-ID: 3489, 9606

UniProt: P24592

Pathways: WNT Signalweg, Myometrial Relaxation and Contraction