FZD4 Antikörper (Internal Region)
Kurzübersicht für FZD4 Antikörper (Internal Region) (ABIN374922)
Target
Alle FZD4 Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
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Bindungsspezifität
- Internal Region
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Spezifität
- This antibody reacts to Frizzled 4.
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Kreuzreaktivität (Details)
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Species reactivity (expected):Rat.
Species reactivity (tested):Human. -
Aufreinigung
- Affinity chromatography
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Immunogen
- Peptide with sequence DEEERRCDPIRIS, from the internal region of the protein sequence
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Applikationshinweise
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Peptide ELISA: 1/16000. Western Blot: 0.3 - 1 μg/mL.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. -
Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Konzentration
- 0,5 mg/mL
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Buffer
- Tris saline, 0.02 % sodium azide, pH 7.3 with 0.5 % bovine serum albumin
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Konservierungsmittel
- Sodium azide
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Vorsichtsmaßnahmen
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Handhabung
- Avoid repeated freezing and thawing.
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Lagerung
- 4 °C/-20 °C
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Informationen zur Lagerung
- Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
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: "Wnt pathway-related gene expression in inflammatory bowel disease." in: Digestive diseases and sciences, Vol. 53, Issue 4, pp. 1013-9, (2008) (PubMed).
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- FZD4 (Frizzled Family Receptor 4 (FZD4))
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Andere Bezeichnung
- CD344 / FZD4 / Frizzled-4
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Hintergrund
- Frizzled 4 is a member of the frizzled gene family. Members of this family encode seven transmembrane domain proteins that are receptors for the Wingless type MMTV integration site family of signaling proteins. Most frizzled receptors are coupled to the beta catenin canonical signaling pathway. This protein may play a role as a positive regulator of the Wingless type MMTV integration site signaling pathway. A transcript variant retaining intronic sequence and encoding a shorter isoform has been described, however, its expression is not supported by other experimental evidence.Synonyms: Fz-4, FzE4, hFz4
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Gen-ID
- 8322
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NCBI Accession
- NP_036325
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UniProt
- Q9ULV1
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Pathways
- WNT Signalweg, Hormone Transport, Sensory Perception of Sound
Target
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