EGR4 Antikörper (Internal Region)

Produktnummer ABIN374881

Dieser Ziege Polyklonal Antikörper detektiert spezifisch EGR4 in WB. Es zeigt Reaktivität gegenüber Proben von Human.

Kurzübersicht für EGR4 Antikörper (Internal Region) (ABIN374881)

Target: EGR4 (Early Growth Response 4 (EGR4))

Reaktivität: Human

Wirt: Ziege

Klonalität: Polyklonal

Konjugat: Dieser EGR4 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktdetails anti-EGR4 Antikörper

Bindungsspezifität: Internal Region

Sequenz: NCGSQGDYQA APE

Kreuzreaktivität (Details): Species reactivity (tested):Human

Aufreinigung: Ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide

Immunogen: Peptide from the internal region of the protein sequence according to NP_001956.2

Anwendungsinformationen

Applikationshinweise: Peptide ELISA: limit dilution 1: 4000. Western blot: 0.3-1 μg/mL. Approx 50 kDa band observed in Human Brain (Cerebellum andFrontal Cortex) lysates (calculated MW of 50.0 kDa according to NP_001956.2).
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 0.5 mg/mL

Buffer: Tris saline, 0.02 % sodium azide, pH 7.3 with 0.5 % bovine serum albumin

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freezing and thawing.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: Store the antibody at 2 - 8 °C up to one month or (in aliquots) at -20 °C for longer.

Details zu EGR4

Target: EGR4 (Early Growth Response 4 (EGR4))

Andere Bezeichnung: EGR4

Hintergrund: EGR4(Early Growth Response protein 4) is a zinc-finger transcription factor that activates the transcription of genes whose products are required for mitogenesis and differentiation. EGR4 is closely related to nerve growth factor-induced clone A (NGFI-A or EGR1), EGR2, and EGR3. These four early response (immediate early) proteins all contain very similar zinc-finger DNA binding domains and five highly homologous subdomains. EGR4 functionally cooperate with NFAT proteins and induce expression of IL2 and TNFalpha. Early growth response proteins (EGR) and nuclear factors of activated T cells (NFAT) form heterodimers and regulate proinflammatory cytokine gene expression.Synonyms: AT133, EGR-4, Early growth response protein 4, NGFI-C, NGFIC, PAT133

Gen-ID: 9606

UniProt: Q05215