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EGR4 Antikörper (C-Term)

EGR4 Reaktivität: Human, Maus, Ratte, Hund, Kaninchen, Rind (Kuh), Meerschweinchen, Pferd, Zebrafisch (Danio rerio) WB Wirt: Kaninchen Polyclonal unconjugated
Produktnummer ABIN2780389
  • Target Alle EGR4 Antikörper anzeigen
    EGR4 (Early Growth Response 4 (EGR4))
    Bindungsspezifität
    • 1
    • 1
    • 1
    • 1
    • 1
    C-Term
    Reaktivität
    • 16
    • 16
    • 5
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Human, Maus, Ratte, Hund, Kaninchen, Rind (Kuh), Meerschweinchen, Pferd, Zebrafisch (Danio rerio)
    Wirt
    • 17
    • 1
    Kaninchen
    Klonalität
    • 18
    Polyklonal
    Konjugat
    • 11
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser EGR4 Antikörper ist unkonjugiert
    Applikation
    • 10
    • 5
    • 5
    • 1
    • 1
    Western Blotting (WB)
    Sequenz
    RSDHLTSHVR THTGEKPFAC DVCGRRFARS DEKKRHSKVH LKQKARAEER
    Homologie
    Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 91%
    Produktmerkmale
    This is a rabbit polyclonal antibody against EGR4. It was validated on Western Blot using a cell lysate as a positive control.
    Aufreinigung
    Affinity Purified
    Immunogen
    The immunogen is a synthetic peptide directed towards the C terminal region of human EGR4
    Top Product
    Discover our top product EGR4 Primärantikörper
  • Applikationshinweise
    Optimal working dilutions should be determined experimentally by the investigator.
    Kommentare

    Antigen size: 486 AA

    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Konzentration
    Lot specific
    Buffer
    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Handhabung
    Avoid repeated freeze-thaw cycles.
    Lagerung
    -20 °C
    Informationen zur Lagerung
    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • Target
    EGR4 (Early Growth Response 4 (EGR4))
    Andere Bezeichnung
    EGR4 (EGR4 Produkte)
    Synonyme
    EGR4 antikoerper, NGFI-C antikoerper, NGFIC antikoerper, PAT133 antikoerper, NGF1-C antikoerper, pAT133 antikoerper, Egr4l1 antikoerper, early growth response 4 antikoerper, EGR4 antikoerper, Egr4 antikoerper
    Hintergrund
    The nerve growth factor-induced clone C (NGFI-C/EGR4) gene is a zinc-finger transcription factor that is rapidly induced by nerve growth factor in rat pheochromocytoma PC12 cells and by seizure in brain. NGFI-C/EGR4 is closely related to the previously described early response genes, nerve growth factor-induced clone A (NGFI-A or EGR1), EGR2, and EGR3. These four early response (immediate early) proteins all contain very similar zinc-finger DNA binding domains and five highly homologous subdomains. EGR-4 functionally cooperate with NFAT proteins and induce expression of IL-2 and TNFalpha. Early growth response proteins (EGR) and nuclear factors of activated T cells (NFAT) form heterodimers and regulate proinflammatory cytokine gene expression.
    Alias Symbols: NGFIC, NGFI-C, PAT133
    Protein Interaction Partner: NFATC2,
    Protein Size: 486
    Molekulargewicht
    51 kDa
    Gen-ID
    1961
    NCBI Accession
    NM_001965, NP_001956
    UniProt
    Q05215
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