GPSM2 Antikörper (Internal Region)

Produktnummer ABIN374868

Produktdetails anti-GPSM2 Antikörper

Target: GPSM2 (G-Protein Signaling Modulator 2 (GPSM2))

Bindungsspezifität: Internal Region

Reaktivität: Human, Hund

Wirt: Ziege

Klonalität: Polyklonal

Konjugat: Dieser GPSM2 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Sequenz: C-NRLKGKKYKT NSSTK

Spezifität: This antibody detects GPSM2.

Kreuzreaktivität (Details): Species reactivity (expected):DogSpecies reactivity (tested):Human

Aufreinigung: Ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide

Immunogen: Peptide from the internal region of the protein sequence according to NP_037428.2 Genename: GPSM2

Anwendungsinformationen

Applikationshinweise: Peptide ELISA: antibody detection limit dilution 1: 64000. Western blot: 0.01-0.03 μg/mL. Approx 70 kDa band observed in Human Brain (Cerebellum)and Human Liver lysates (calculated MW of 75.0 kDa according to NP_037428.2). Anadditional band of unknown identity was also consistently observed at 26-20 kDa. Thisband was successfully blocked by incubation with the immunising peptide. We wouldappreciate any feedback from people in the field - have any such results been reportedwith other antibodies/lysates? Have any further splice variants/modified forms beenreported?
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 0.5 mg/mL

Buffer: Tris saline, 0.02 % sodium azide, pH 7.3 with 0.5 % bovine serum albumin

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freezing and thawing.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: Store the antibody at 2 - 8 °C up to one month or (in aliquots) at -20 °C for longer.

Details zu GPSM2

Target: GPSM2 (G-Protein Signaling Modulator 2 (GPSM2))

Andere Bezeichnung: GPSM2 (GPSM2 Produkte)

Synonyme: CMCS antikoerper, DFNB82 antikoerper, LGN antikoerper, PINS antikoerper, dfnb82 antikoerper, lgn antikoerper, pins antikoerper, RGD1560967 antikoerper, Pinsa antikoerper, zgc:63574 antikoerper, 6230410J09Rik antikoerper, Pins antikoerper, G protein signaling modulator 2 antikoerper, G-protein signaling modulator 2 S homeolog antikoerper, G-protein signaling modulator 2 antikoerper, G-protein signalling modulator 2 (AGS3-like, C. elegans) antikoerper, GPSM2 antikoerper, gpsm2.S antikoerper, Gpsm2 antikoerper, gpsm2 antikoerper

Hintergrund: GPSM2 plays an important role in spindle pole orientation. It interacts and contributes to the functional activity of G(i) alpha proteins. GPSM2 acts to stabilize the apical complex during neuroblast divisions.Synonyms: G-protein-signaling modulator 2, GPSM-2, LGN, Mosaic protein LGN

Gen-ID: 29899

NCBI Accession: NP_037428

UniProt: P81274

Pathways: Regulation of G-Protein Coupled Receptor Protein Signaling