GPSM2 Antikörper (Internal Region)
Kurzübersicht für GPSM2 Antikörper (Internal Region) (ABIN374868)
Target
Alle GPSM2 Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
-
-
Bindungsspezifität
- Internal Region
-
Sequenz
- C-NRLKGKKYKT NSSTK
-
Spezifität
- This antibody detects GPSM2.
-
Kreuzreaktivität (Details)
- Species reactivity (expected):DogSpecies reactivity (tested):Human
-
Aufreinigung
- Ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide
-
Immunogen
- Peptide from the internal region of the protein sequence according to NP_037428.2 Genename: GPSM2
-
-
-
-
Applikationshinweise
-
Peptide ELISA: antibody detection limit dilution 1: 64000. Western blot: 0.01-0.03 μg/mL. Approx 70 kDa band observed in Human Brain (Cerebellum)and Human Liver lysates (calculated MW of 75.0 kDa according to NP_037428.2). Anadditional band of unknown identity was also consistently observed at 26-20 kDa. Thisband was successfully blocked by incubation with the immunising peptide. We wouldappreciate any feedback from people in the field - have any such results been reportedwith other antibodies/lysates? Have any further splice variants/modified forms beenreported?
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. -
Beschränkungen
- Nur für Forschungszwecke einsetzbar
-
-
-
Konzentration
- 0.5 mg/mL
-
Buffer
- Tris saline, 0.02 % sodium azide, pH 7.3 with 0.5 % bovine serum albumin
-
Konservierungsmittel
- Sodium azide
-
Vorsichtsmaßnahmen
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
Handhabung
- Avoid repeated freezing and thawing.
-
Lagerung
- 4 °C/-20 °C
-
Informationen zur Lagerung
- Store the antibody at 2 - 8 °C up to one month or (in aliquots) at -20 °C for longer.
-
-
- GPSM2 (G-Protein Signaling Modulator 2 (GPSM2))
-
Andere Bezeichnung
- GPSM2
-
Hintergrund
- GPSM2 plays an important role in spindle pole orientation. It interacts and contributes to the functional activity of G(i) alpha proteins. GPSM2 acts to stabilize the apical complex during neuroblast divisions.Synonyms: G-protein-signaling modulator 2, GPSM-2, LGN, Mosaic protein LGN
-
Gen-ID
- 29899
-
NCBI Accession
- NP_037428
-
UniProt
- P81274
-
Pathways
- Regulation of G-Protein Coupled Receptor Protein Signaling
Target
-