Kallikrein 1 Antikörper (Internal Region)

Produktnummer ABIN374847

Produktdetails anti-Kallikrein 1 Antikörper

Target: Kallikrein 1 (KLK1)

Bindungsspezifität: Internal Region

Reaktivität: Human

Wirt: Ziege

Klonalität: Polyklonal

Konjugat: Dieser Kallikrein 1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Spezifität: This antibody reacts to KLK1.

Aufreinigung: Affinity chromatography

Immunogen: Peptide with sequence PNDECKKAHVQK, from the internal region of the protein sequence

Anwendungsinformationen

Applikationshinweise: Peptide ELISA: 1/2000. Western Blot: 1 - 3 μg/mL.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 0,5 mg/mL

Buffer: Tris saline, 0.02 % sodium azide, pH 7.3 with 0.5 % bovine serum albumin

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freezing and thawing.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Details zu Kallikrein 1

Target: Kallikrein 1 (KLK1)

Andere Bezeichnung: KLK1 / Kallikrein-1 (KLK1 Produkte)

Synonyme: KLKR antikoerper, Klk6 antikoerper, hK1 antikoerper, klkr antikoerper, kallikrein antikoerper, 0610007D04Rik antikoerper, Kal antikoerper, Klk1b6 antikoerper, mGk-6 antikoerper, kallikrein 1 antikoerper, kallikrein 1 L homeolog antikoerper, KLK1 antikoerper, klk1.L antikoerper, LOC100101620 antikoerper, Klk1 antikoerper

Hintergrund: Kallikreins are a subgroup of serine proteases having diverse physiological functions. Growing evidence suggests that many kallikreins are implicated in carcinogenesis and some have potential as novel cancer and other disease biomarkers. Kallikrein 1 releases the vasoactive peptide, Lys-bradykinin, from low molecular weight kininogen. Low renal synthesis and urinary excretion of tissue kallikrein have been linked to hypertension in animals and humans and the kallikrein-kinin system may be involved in the development or progression of cardiovascular disease.Synonyms: EC 3.4.21.35, KLK-1, Kallikrein1, Kidney/pancreas/salivary gland kallikrein, Tissue kallikrein

Gen-ID: 3816

NCBI Accession: NP_002248

UniProt: P06870

Pathways: Komplementsystem