Kallikrein 2 Antikörper (Internal Region)
Kurzübersicht für Kallikrein 2 Antikörper (Internal Region) (ABIN374827)
Target
Alle Kallikrein 2 (KLK2) Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
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Bindungsspezifität
- Internal Region
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Sequenz
- C-KHQSLRPDED SSHD
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Spezifität
- This antibody is expected to recognize both reported isoforms of Human KLK2 (NP_005542.1, NP_001002231.1).
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Aufreinigung
- Ammonium Sulphate Precipitation followed by antigen Affinity Chromatography using the immunizing peptide
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Immunogen
- Peptide with sequence from the internal region of the protein sequence according to NP_005542.1, NP_001002231.1. Genename: KLK2
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Applikationshinweise
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Peptide ELISA: 1/16000. Western Blot: 0.1 - 0.3 μg/mL.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. -
Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Konzentration
- 0.5 mg/mL
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Buffer
- Tris buffered saline, pH ~7.3 containing 0.02 % Sodium Azide as preservative and 0.5 % BSA as stabilizer
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Konservierungsmittel
- Sodium azide
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Vorsichtsmaßnahmen
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Handhabung
- Avoid repeated freezing and thawing.
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Lagerung
- 4 °C/-20 °C
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Informationen zur Lagerung
- Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
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- Kallikrein 2 (KLK2)
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Andere Bezeichnung
- KLK2 / Kallikrein-2
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Hintergrund
- Kallikreins (KLKs) are a subgroup of trypsin-like serine proteases and are implicated in carcinogenesis. Kallikrein 2 is most closely related to Kallikrein 3 (PSA), with 78 % identity and with kallikrein 1, at 68 % identity. Like Kallikrein 3, Kallikrein 2 is found in greatest abundance in the prostate, but at much lower levels than Kallikrein 3. In addition, Kallikrein 2 seems to be more labile than Kallikrein 1 or Kallikrein 3 and is often found in a cleaved form. Kallikrein 2 is inhibited by Protein C Inhibitor (PCI).Synonyms: Glandular kallikrein-1, Kallikrein 2, Kallikrein2, Tissue kallikrein-2, hGK-1, hK2
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Gen-ID
- 3817
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NCBI Accession
- NP_001002231
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UniProt
- P20151
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Pathways
- Komplementsystem
Target
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