VANGL2 Antikörper (Internal Region)

Produktnummer ABIN374805

Produktdetails anti-VANGL2 Antikörper

Target: VANGL2 (Vang-Like 2 (VANGL2))

Bindungsspezifität: Internal Region

Reaktivität: Human, Maus

Wirt: Ziege

Klonalität: Polyklonal

Konjugat: Dieser VANGL2 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Sequenz: C-QKYLRTTKQQ PYH

Spezifität: This antibody detects Vang-like protein 2 (VANGL2).

Kreuzreaktivität (Details): Species reactivity (expected):Cow, ZebrafishSpecies reactivity (tested):Human, Mouse

Aufreinigung: Ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide

Immunogen: Peptide from the internal region of the protein sequence according to NP_065068.1 Genename: VANGL2

Anwendungsinformationen

Applikationshinweise: Peptide ELISA: antibody detection limit dilution 1: 32000. Western blot: 0.3-1 μg/mL. Approx 55 kDa band observed in Human Lung and Mouse Brainlysates (calculated MW of 59.5 kDa according to NP_065068.1).
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 0.5 mg/mL

Buffer: Tris saline, 0.02 % sodium azide, pH 7.3 with 0.5 % bovine serum albumin

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freezing and thawing.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: Store at 2 - 8 °C for up to one month or (in aliquots) at -20 °C.

Details zu VANGL2

Target: VANGL2 (Vang-Like 2 (VANGL2))

Andere Bezeichnung: Vang-Like Protein 2 (VANGL2) (VANGL2 Produkte)

Synonyme: Strabismus antikoerper, lpp1 antikoerper, ltap antikoerper, stb1 antikoerper, stbm antikoerper, stbm1 antikoerper, VANGL2 antikoerper, LPP1 antikoerper, LTAP antikoerper, STB1 antikoerper, STBM antikoerper, STBM1 antikoerper, C530001F03Rik antikoerper, Lp antikoerper, Lpp1 antikoerper, Ltap antikoerper, Vang1l2 antikoerper, loop-tail antikoerper, ska17 antikoerper, ska antikoerper, strabismus antikoerper, tri antikoerper, vang antikoerper, vangl2 antikoerper, vangl2b antikoerper, vangl2a antikoerper, VANGL planar cell polarity protein 2 antikoerper, vang-like 2 (van gogh, Drosophila) antikoerper, VANGL planar cell polarity protein 2 S homeolog antikoerper, VANGL planar cell polarity protein 2 L homeolog antikoerper, vangl2 antikoerper, VANGL2 antikoerper, Vangl2 antikoerper, vangl2.S antikoerper, vangl2.L antikoerper

Hintergrund: VANGL2 is involved in the control of early morphogenesis and patterning of both axial midline structures and the development of neural plate. It plays a role in the regulation of planar cell polarity, particularly in the orientation of stereociliary bundles in the cochlea. It is required for polarization and movement of myocardializing cells in the outflow tract and seems to act via RHOA signaling to regulate this process.Synonyms: KIAA1215, Loop-tail protein 1 homolog, STB1, Strabismus 1, Van Gogh-like protein 2

Gen-ID: 57216, 9606

UniProt: Q9ULK5

Pathways: WNT Signalweg, Stem Cell Maintenance, Tube Formation, Asymmetric Protein Localization