VANGL2 Antikörper (Internal Region)

Produktnummer ABIN374805

Der Ziege Polyklonal anti-VANGL2 Antikörper (ABIN374805) detektiert spezifisch VANGL2 in WB. Dieser Antikörper reagiert spezifisch mit Proben aus Human und Maus.

Kurzübersicht für VANGL2 Antikörper (Internal Region) (ABIN374805)

Target: VANGL2 (Vang-Like 2 (VANGL2))

Reaktivität: Human, Maus

Wirt: Ziege

Klonalität: Polyklonal

Konjugat: Dieser VANGL2 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktdetails anti-VANGL2 Antikörper

Bindungsspezifität: Internal Region

Sequenz: C-QKYLRTTKQQ PYH

Spezifität: This antibody detects Vang-like protein 2 (VANGL2).

Kreuzreaktivität (Details): Species reactivity (expected):Cow, ZebrafishSpecies reactivity (tested):Human, Mouse

Aufreinigung: Ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide

Immunogen: Peptide from the internal region of the protein sequence according to NP_065068.1 Genename: VANGL2

Anwendungsinformationen

Applikationshinweise: Peptide ELISA: antibody detection limit dilution 1: 32000. Western blot: 0.3-1 μg/mL. Approx 55 kDa band observed in Human Lung and Mouse Brainlysates (calculated MW of 59.5 kDa according to NP_065068.1).
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 0.5 mg/mL

Buffer: Tris saline, 0.02 % sodium azide, pH 7.3 with 0.5 % bovine serum albumin

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freezing and thawing.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: Store at 2 - 8 °C for up to one month or (in aliquots) at -20 °C.

Details zu VANGL2

Target: VANGL2 (Vang-Like 2 (VANGL2))

Andere Bezeichnung: Vang-Like Protein 2 (VANGL2)

Hintergrund: VANGL2 is involved in the control of early morphogenesis and patterning of both axial midline structures and the development of neural plate. It plays a role in the regulation of planar cell polarity, particularly in the orientation of stereociliary bundles in the cochlea. It is required for polarization and movement of myocardializing cells in the outflow tract and seems to act via RHOA signaling to regulate this process.Synonyms: KIAA1215, Loop-tail protein 1 homolog, STB1, Strabismus 1, Van Gogh-like protein 2

Gen-ID: 57216, 9606

UniProt: Q9ULK5

Pathways: WNT Signalweg, Stem Cell Maintenance, Tube Formation, Asymmetric Protein Localization