CNR2 Antikörper (C-Term)

Produktnummer ABIN374612

Der Ziege Polyklonal Anti-CNR2-Antikörper wurde für WB validiert. Er ist geeignet, CNR2 in Proben von Human zu detektieren.

Kurzübersicht für CNR2 Antikörper (C-Term) (ABIN374612)

Target: CNR2 (Cannabinoid Receptor 2 (CNR2))

Reaktivität: Human

Wirt: Ziege

Klonalität: Polyklonal

Konjugat: Dieser CNR2 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktdetails anti-CNR2 Antikörper

Bindungsspezifität: C-Term

Spezifität: This antibody reacts to Cannabinoid receptor 2.

Aufreinigung: Affinity chromatography

Immunogen: Peptide with sequence C-TETEADGKITPWPD, from the C Terminus of the protein sequence

Anwendungsinformationen

Applikationshinweise: Peptide ELISA: 1/16000. Western Blot: 2 - 3 μg/mL.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 0,5 mg/mL

Buffer: Tris saline, 0.02 % sodium azide, pH 7.3 with 0.5 % bovine serum albumin

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freezing and thawing.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Details zu CNR2

Target: CNR2 (Cannabinoid Receptor 2 (CNR2))

Andere Bezeichnung: Cannabinoid Receptor 2

Hintergrund: The cannabinoid delta-9-tetrahydrocannabinol is the principal psychoactive ingredient of marijuana. The proteins encoded by this gene and the cannabinoid receptor 1 (brain) (CNR1) gene have the characteristics of a guanine nucleotide-binding protein (G-protein)-coupled receptor for cannabinoids. They inhibit adenylate cyclase activity in a dose-dependent, stereoselective, and pertussis toxin-sensitive manner. These proteins have been found to be involved in the cannabinoid-induced CNS effects (including alterations in mood and cognition) experienced by users of marijuana. The cannabinoid receptors are members of family 1 of the G-protein-coupled receptors. Cannabinoids exert their well known physiological effects through two G protein coupled receptors, cannabinoid receptor 1 (CB1) and CB2. Both cannabinoid receptors have been shown to inhibit adenylyl cyclase as well as stimulate the mitogen-activated protein kinase, MAPK. CB1 receptors also modulate ion channels through direct G-protein interactions. Delta 9-tetrahydrocannibinol and related ligands likely exert their psychoactive effects by inhibiting presynaptic N- and P / Q type calcium channels. CB2 is thought to function primarily in the immune system although it has been suggested to be present in the central nervous system, including the retina.Synonyms: CB-2, CB2, CNR2, CX5, hCB2

Gen-ID: 1269, 9606

UniProt: P34972