CCKBR Antikörper (Internal Region)

Produktnummer ABIN374567

Der Ziege Polyklonal anti-CCKBR Antikörper wird verwendet zum Nachweis von CCKBR in Proben von Human, Maus, Ratte und Rind (Kuh). Er wurde validiert für WB, IHC (p), IF und EIA.

Kurzübersicht für CCKBR Antikörper (Internal Region) (ABIN374567)

Target: CCKBR (Cholecystokinin B Receptor (CCKBR))

Reaktivität: Human, Maus, Ratte, Rind (Kuh)

Wirt: Ziege

Klonalität: Polyklonal

Konjugat: Dieser CCKBR Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (IF), Enzyme Immunoassay (EIA)

Produktdetails anti-CCKBR Antikörper

Bindungsspezifität: Internal Region

Sequenz: C-FDGDSDSDSQ SRVRNQ

Spezifität: This antibody recognizes CCK-B Receptor.

Kreuzreaktivität (Details): Species reactivity (expected):Mouse, Bovine.
Species reactivity (tested):Human, Rat.

Aufreinigung: Ammonium Sulphate Precipitation followed by Antigen Affinity Chromatography using the immunizing peptide

Immunogen: Peptide with sequence from the internal region of the protein sequence according to NP_795344.1. Genename: CCKBR

Anwendungsinformationen

Applikationshinweise: Peptide ELISA: 1/32000. Western Blot: 0.1 - 0.3 μg/mL. Immunohistochemistry on paraffin sections: 3 μg/mL.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 0.5 mg/mL

Buffer: Tris saline, pH ~7.3, 0.02 % Sodium Azide, 0.5 % BSA

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freezing and thawing.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: Store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Details zu CCKBR

Target: CCKBR (Cholecystokinin B Receptor (CCKBR))

Andere Bezeichnung: CCK-B Receptor

Hintergrund: CCKBR is a G protein coupled receptor for gastrin and cholecystokinin (CCK), regulatory peptides of the brain and gastrointestinal tract. This protein is a type B gastrin receptor, which has a high affinity for both sulfated and nonsulfated CCK analogs and is found principally in the central nervous system and the gastrointestinal tract. A misspliced transcript variant including an intron has been observed in cells from colorectal and pancreatic tumors. CCKBR is most abundant in brain and stomach but it can also be found in colon, pancreas, thyroid, and various cancers.Synonyms: CCK-BR, CCK2-R, CCKB Receptor, CCKBR, CCKRB, Cholecystokinin type B receptor, Cholecystokinin-2 receptor, Gastrin/cholecystokinin type B receptor

Gen-ID: 887, 9606

UniProt: P32239

Pathways: Positive Regulation of Peptide Hormone Secretion, Feeding Behaviour